Long-term ambient air pollution exposure and self-reported morbidity in the Australian Longitudinal Study on Women’s Health: a cross-sectional study

Lazarevic, Nina, Dobson, Annette J., Barnett, Adrian G. and Knibbs, Luke D. (2015) Long-term ambient air pollution exposure and self-reported morbidity in the Australian Longitudinal Study on Women’s Health: a cross-sectional study. BMJ Open, 5 10: 1-10. doi:10.1136/bmjopen-2015-008714


Author Lazarevic, Nina
Dobson, Annette J.
Barnett, Adrian G.
Knibbs, Luke D.
Title Long-term ambient air pollution exposure and self-reported morbidity in the Australian Longitudinal Study on Women’s Health: a cross-sectional study
Journal name BMJ Open   Check publisher's open access policy
ISSN 2044-6055
Publication date 2015-10-26
Sub-type Article (original research)
DOI 10.1136/bmjopen-2015-008714
Open Access Status DOI
Volume 5
Issue 10
Start page 1
End page 10
Total pages 10
Place of publication London, United Kingdom
Publisher B M J Group
Collection year 2016
Language eng
Formatted abstract
Objective:  We sought to assess the effect of long-term exposure to ambient air pollution on the prevalence of self-reported health outcomes in Australian women.

Design:  Cross-sectional study.

Setting and participants:  The geocoded residential addresses of 26 991 women across 3 age cohorts in the Australian Longitudinal Study on Women's Health between 2006 and 2011 were linked to nitrogen dioxide (NO2) exposure estimates from a land-use regression model. Annual average NO2 concentrations and residential proximity to roads were used as proxies of exposure to ambient air pollution.

Outcome measures:  Self-reported disease presence for diabetes mellitus, heart disease, hypertension, stroke, asthma, chronic obstructive pulmonary disease and self-reported symptoms of allergies, breathing difficulties, chest pain and palpitations.

Methods:  Disease prevalence was modelled by population-averaged Poisson regression models estimated by generalised estimating equations. Associations between symptoms and ambient air pollution were modelled by multilevel mixed logistic regression. Spatial clustering was accounted for at the postcode level.

Results:  No associations were observed between any of the outcome and exposure variables considered at the 1% significance level after adjusting for known risk factors and confounders.

Conclusions:  Long-term exposure to ambient air pollution was not associated with self-reported disease prevalence in Australian women. The observed results may have been due to exposure and outcome misclassification, lack of power to detect weak associations or an actual absence of associations with self-reported outcomes at the relatively low annual average air pollution exposure levels across Australia.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Public Health Publications
 
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Created: Fri, 25 Sep 2015, 08:27:00 EST by Luke Knibbs on behalf of School of Public Health