Sensitivity and specificity of a five-minute cognitive screen in heart failure patients

Cameron, Janette, Gallagher, Robyn, Pressler, Susan J., McLenna, Skye N., Ski, Chantal F., Tofler, Geoffrey and Thompson, David R. (2016) Sensitivity and specificity of a five-minute cognitive screen in heart failure patients. Journal of Cardiac Failure, 22 2: 99-107. doi:10.1016/j.cardfail.2015.08.343

Author Cameron, Janette
Gallagher, Robyn
Pressler, Susan J.
McLenna, Skye N.
Ski, Chantal F.
Tofler, Geoffrey
Thompson, David R.
Title Sensitivity and specificity of a five-minute cognitive screen in heart failure patients
Journal name Journal of Cardiac Failure   Check publisher's open access policy
ISSN 1071-9164
Publication date 2016-02
Sub-type Article (original research)
DOI 10.1016/j.cardfail.2015.08.343
Volume 22
Issue 2
Start page 99
End page 107
Total pages 33
Place of publication Philadelphia, PA United States
Publisher Churchill Livingstone
Collection year 2017
Language eng
Formatted abstract
Cognitive impairment occurs in up to 80% of heart failure (HF) patients. The National Institute for Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network (CSN) recommend a five-minute cognitive screening protocol, yet to be psychometrically evaluated in HF populations.

To conduct a secondary analysis of the sensitivity and specificity of the NINDS-CSN brief cognitive screening protocol in HF patients.

The Montreal Cognitive Assessment (MoCA) was administered to 221 HF patients. The NINDS-CSN screen comprises three MoCA items; lower scores indicating poorer cognitive function. Receiver operator characteristic (ROC) curves were constructed, determining the sensitivity, specificity and appropriate cut-off scores of the NINDS-CSN screen.

In a HF population aged 76±12 years, 136 (62%) were characterised with cognitive impairment (MoCA <26). Scores on the NINDS-CSN screen ranged from 3-11. The area under the ROC curve indicated good accuracy in screening for cognitive impairment (0.88, p<0.01, 95% CI 0.83 to 0.92). The cut-off score ≤9 provided 89% sensitivity and 71% specificity.

The NINDS-CSN protocol offers clinicians a feasible telephone method to screen for cognitive impairment in HF patients. Future studies should include a neuropsychological battery to more comprehensively examine the diagnostic accuracy of brief cognitive screening protocols
Keyword Heart failure
Cognitive impairment
Cognitive screening
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Nursing, Midwifery and Social Work Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 2 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 24 Sep 2015, 08:41:03 EST by Vicki Percival on behalf of School of Nursing, Midwifery and Social Work