Green and black cardamom in a diet-induced rat model of metabolic syndrome

Bhaswant, Maharshi, Poudyal, Hemant, Mathai, Michael L., Ward, Leigh C., Mouatt, Peter and Brown, Lindsay (2015) Green and black cardamom in a diet-induced rat model of metabolic syndrome. Nutrients, 7 9: 7691-7707. doi:10.3390/nu7095360

Author Bhaswant, Maharshi
Poudyal, Hemant
Mathai, Michael L.
Ward, Leigh C.
Mouatt, Peter
Brown, Lindsay
Title Green and black cardamom in a diet-induced rat model of metabolic syndrome
Journal name Nutrients   Check publisher's open access policy
ISSN 2072-6643
Publication date 2015-09-11
Year available 2015
Sub-type Article (original research)
DOI 10.3390/nu7095360
Open Access Status DOI
Volume 7
Issue 9
Start page 7691
End page 7707
Total pages 434
Place of publication Basel, Switzerland
Publisher MDPI AG
Collection year 2016
Language eng
Abstract Both black (B) and green (G) cardamom are used as flavours during food preparation. This study investigated the responses to B and G in a diet-induced rat model of human metabolic syndrome. Male Wistar rats were fed either a corn starch-rich diet (C) or a high-carbohydrate, high-fat diet with increased simple sugars along with saturated and trans fats (H) for 16 weeks. H rats showed signs of metabolic syndrome leading to visceral obesity with hypertension, glucose intolerance, cardiovascular remodelling and nonalcoholic fatty liver disease. Food was supplemented with 3% dried B or G for the final eight weeks only. The major volatile components were the closely related terpenes, 1,8-cineole in B and α-terpinyl acetate in G. HB (high-carbohydrate, high-fat + black cardamom) rats showed marked reversal of diet-induced changes, with decreased visceral adiposity, total body fat mass, systolic blood pressure and plasma triglycerides, and structure and function of the heart and liver. In contrast, HG (high-carbohydrate, high-fat + green cardamom) rats increased visceral adiposity and total body fat mass, and increased heart and liver damage, without consistent improvement in the signs of metabolic syndrome. These results suggest that black cardamom is more effective in reversing the signs of metabolic syndrome than green cardamom.
Keyword Cardamom
Metabolic syndrome
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
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