Precocious puberty secondary to massive ovarian oedema in a 6-month-old girl

Natarajan, A, Wales, JKH, Marven, SS and Wright, NP (2004) Precocious puberty secondary to massive ovarian oedema in a 6-month-old girl. European Journal of Endocrinology, 150 2: 119-123. doi:10.1530/eje.0.1500119


Author Natarajan, A
Wales, JKH
Marven, SS
Wright, NP
Title Precocious puberty secondary to massive ovarian oedema in a 6-month-old girl
Journal name European Journal of Endocrinology   Check publisher's open access policy
ISSN 0804-4643
Publication date 2004
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1530/eje.0.1500119
Volume 150
Issue 2
Start page 119
End page 123
Total pages 5
Language eng
Subject 1310 Endocrinology
Abstract A 6-month-old girl was referred with breast and pubic hair development. Investigations excluded an adrenal or central cause for her precocity. Ovarian ultrasound scans showed bilaterally enlarged ovaries with both solid and cystic changes. A follow-up examination suggested progression of the precocity and in view of the young age of the child, and concerns regarding underlying malignancy, she underwent laparotomy. Histology showed no evidence of neoplasia but there was stromal oedema consistent with a diagnosis of massive ovarian oedema. This entity is poorly recognised in the paediatric literature as a cause of sexual precocity, and has never previously been described in such a young patient. This is an unusual cause of precocity in a young child and its recognition and management are reviewed.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
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