Zinc and cardiovascular disease

Little, Peter J., Bhattacharya, Runa, Moreyra, Abel E. and Korichneva, Irina L. (2010) Zinc and cardiovascular disease. Nutrition, 26 11-12: 1050-1057. doi:10.1016/j.nut.2010.03.007


Author Little, Peter J.
Bhattacharya, Runa
Moreyra, Abel E.
Korichneva, Irina L.
Title Zinc and cardiovascular disease
Journal name Nutrition   Check publisher's open access policy
ISSN 0899-9007
1873-1244
Publication date 2010-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.nut.2010.03.007
Open Access Status Not Open Access
Volume 26
Issue 11-12
Start page 1050
End page 1057
Total pages 8
Place of publication New York, NY United States
Publisher Elsevier
Language eng
Abstract Zinc is a vital element in maintaining the normal structure and physiology of cells. The fact that it has an important role in states of cardiovascular diseases has been studied and described by several research groups. It appears to have protective effects in coronary artery disease and cardiomyopathy. Intracellular zinc plays a critical role in the redox signaling pathway, whereby certain triggers such as ischemia and infarction lead to release of zinc from proteins and cause myocardial damage. In such states, replenishing with zinc has been shown to improve cardiac function and prevent further damage. Thus, the area of zinc homeostasis is emerging in cardiovascular disease research. The goal of this report is to review the current knowledge and suggest further avenues of research.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Pharmacy Publications
 
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