Motor organization of positive and negative emotional vocalization in the cat midbrain periaqueductal gray

Subramanian, Hari H., Arun, Mridula, Silburn, Peter A. and Holstege, Gert (2015) Motor organization of positive and negative emotional vocalization in the cat midbrain periaqueductal gray. The Journal Of Comparative Neurology, 524 8: 1540-1557. doi:10.1002/cne.23869

Author Subramanian, Hari H.
Arun, Mridula
Silburn, Peter A.
Holstege, Gert
Title Motor organization of positive and negative emotional vocalization in the cat midbrain periaqueductal gray
Journal name The Journal Of Comparative Neurology   Check publisher's open access policy
ISSN 0021-9967
Publication date 2015
Year available 2015
Sub-type Article (original research)
DOI 10.1002/cne.23869
Open Access Status Not Open Access
Volume 524
Issue 8
Start page 1540
End page 1557
Total pages 18
Place of publication Hoboken, NJ United States
Publisher John Wiley and Sons
Collection year 2016
Language eng
Formatted abstract
Neurochemical microstimulation in different parts of the midbrain periaqueductal gray (PAG) in the cat generates four different types of vocalization, mews, howls, cries, and hisses. Mews signify positive vocal expression, whereas howls, hisses, and cries signify negative vocal communications. Mews were generated in the lateral column of the intermediate PAG and howls and hisses in the ventrolateral column of the intermediate PAG. Cries were generated in two regions, the lateral column of the rostral PAG and the ventrolateral column of the caudal PAG. To define the specific motor patterns belonging to mews, howls, and cries, the following muscles were recorded during these vocalizations: larynx (cricothyroid, thyroarytenoid, and posterior cricoarytenoid), tongue (genioglossus), jaw (digastric), and respiration (diaphragm, internal intercostal, external abdominal oblique, and internal abdominal oblique) muscles. Furthermore, the frequency, intensity, activation cascades, and turns and amplitude analyses of the electromyograms (EMGs) during these vocalizations were analyzed. The results show that each type of vocalization consists of a specific, circumscribed motor coordination. The nucleus retroambiguus (NRA) in the caudal medulla serves as the final premotor interneuronal output system for vocalization. NRA neurochemical microstimulation also generated vocalizations (guttural sounds). Analysis of the EMGs demonstrated that these vocalizations consist of only small parts of the emotional voalizations generated by neurochemical stimulation in the PAG. These results demonstrate that motor organization of positive and negative emotional vocal expressions are segregated in the PAG and that the PAG uses the NRA as a tool to gain access to the motoneurons generating vocalization.
Keyword Nucleus retroambiguus
Midbrain Periaqueductal Gray
Motor organization
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2016 Collection
School of Biomedical Sciences Publications
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Created: Tue, 15 Sep 2015, 10:37:12 EST by Roheen Gill on behalf of UQ Centre for Clinical Research