Preventing depression and anxiety in young people: a review of the joint efficacy of universal, selective and indicated prevention

Stockings, E. A., Degenhardt, L., Dobbins, T., Lee, Y. Y., Erskine, H. E., Whiteford, H. A. and Patton, G. (2015) Preventing depression and anxiety in young people: a review of the joint efficacy of universal, selective and indicated prevention. Psychological Medicine, 46 1: 11-26. doi:10.1017/S0033291715001725


Author Stockings, E. A.
Degenhardt, L.
Dobbins, T.
Lee, Y. Y.
Erskine, H. E.
Whiteford, H. A.
Patton, G.
Title Preventing depression and anxiety in young people: a review of the joint efficacy of universal, selective and indicated prevention
Journal name Psychological Medicine   Check publisher's open access policy
ISSN 1469-8978
0033-2917
Publication date 2015-08-28
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1017/S0033291715001725
Open Access Status Not Open Access
Volume 46
Issue 1
Start page 11
End page 26
Total pages 16
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Collection year 2016
Language eng
Formatted abstract
Depression and anxiety (internalizing disorders) are the largest contributors to the non-fatal health burden among young people. This is the first meta-analysis to examine the joint efficacy of universal, selective, and indicated preventive interventions upon both depression and anxiety among children and adolescents (5–18 years) while accounting for their co-morbidity. We conducted a systematic review of reviews in Medline, PsycINFO and the Cochrane Library of Systematic Reviews, from 1980 to August 2014. Multivariate meta-analysis examined the efficacy of preventive interventions on depression and anxiety outcomes separately, and the joint efficacy on both disorders combined. Meta-regressions examined heterogeneity of effect according to a range of study variables. Outcomes were relative risks (RR) for disorder, and standardized mean differences (Cohen's d) for symptoms. One hundred and forty-six randomized controlled trials (46 072 participants) evaluated universal (children with no identified risk, n = 54) selective (population subgroups of children who have an increased risk of developing internalizing disorders due to shared risk factors, n = 45) and indicated prevention (children with minimal but detectable symptoms of an internalizing disorder, n = 47), mostly using psychological-only strategies (n = 105). Reductions in internalizing disorder onset occurred up to 9 months post-intervention, whether universal [RR 0.47, 95% confidence interval (CI) 0.37–0.60], selective (RR 0.61, 95% CI 0.43–0.85) or indicated (RR 0.48, 95% CI 0.29–0.78). Reductions in internalizing symptoms occurred up to 12 months post-intervention for universal prevention; however, reductions only occurred in the shorter term for selective and indicated prevention. Universal, selective and indicated prevention interventions are efficacious in reducing internalizing disorders and symptoms in the short term. They might be considered as repeated exposures in school settings across childhood and adolescence. (PROSPERO registration: CRD42014013990.)
Keyword Child and adolescent
Anxiety
Depression
Early intervention
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Public Health Publications
 
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