Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)

Xia, Qingyou, Guo, Yiran, Zhang, Ze, Li, Dong, Xuan, Zhaoling, Li, Zhuo, Dai, Fangyin, Li, Yingrui, Cheng, Daojun, Li, Ruiqiang, Cheng, Tingcai, Jiang, Tao, Becquet, Celine, Xu, Xun, Liu, Chun, Zha, Xingfu, Fan, Wei, Lin, Ying, Shen, Yihong, Jiang, Lan, Jensen, Jeffrey, Hellmann, Ines, Tang, Si, Zhao, Ping, Xu, Hanfu, Yu, Chang, Zhang, Guojie, Li, Jun, Cao, Jianjun, Liu, Shiping, He, Ningjia, Zhou, Yan, Liu, Hui, Zhao, Jing, Ye, Chen, Du, Zhouhe, Pan, Guoqing, Zhao, Aichun, Shao, Haojing, Zeng, Wei, Wu, Ping, Li, Chunfeng, Pan, Minhui, Li, Jingjing, Yin, Xuyang, Li, Dawei, Wang, Juan, Zheng, Huisong, Wang, Wen, Zhang, Xiuqing, Li, Songgang, Yang, Huanming, Lu, Cheng, Nielsen, Rasmus, Zhou, Zeyang, Wang, Jian, Xiang, Zhonghuai and Wang, Jun (2009) Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science, 326 5951: 433-436. doi:10.1126/science.1176620


Author Xia, Qingyou
Guo, Yiran
Zhang, Ze
Li, Dong
Xuan, Zhaoling
Li, Zhuo
Dai, Fangyin
Li, Yingrui
Cheng, Daojun
Li, Ruiqiang
Cheng, Tingcai
Jiang, Tao
Becquet, Celine
Xu, Xun
Liu, Chun
Zha, Xingfu
Fan, Wei
Lin, Ying
Shen, Yihong
Jiang, Lan
Jensen, Jeffrey
Hellmann, Ines
Tang, Si
Zhao, Ping
Xu, Hanfu
Yu, Chang
Zhang, Guojie
Li, Jun
Cao, Jianjun
Liu, Shiping
He, Ningjia
Zhou, Yan
Liu, Hui
Zhao, Jing
Ye, Chen
Du, Zhouhe
Pan, Guoqing
Zhao, Aichun
Shao, Haojing
Zeng, Wei
Wu, Ping
Li, Chunfeng
Pan, Minhui
Li, Jingjing
Yin, Xuyang
Li, Dawei
Wang, Juan
Zheng, Huisong
Wang, Wen
Zhang, Xiuqing
Li, Songgang
Yang, Huanming
Lu, Cheng
Nielsen, Rasmus
Zhou, Zeyang
Wang, Jian
Xiang, Zhonghuai
Wang, Jun
Title Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)
Formatted title
Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)
Journal name Science   Check publisher's open access policy
ISSN 0036-8075
1095-9203
Publication date 2009-10-16
Sub-type Article (original research)
DOI 10.1126/science.1176620
Open Access Status Not yet assessed
Volume 326
Issue 5951
Start page 433
End page 436
Total pages 4
Place of publication Washington, DC, United States
Publisher American Association for the Advancement of Science
Language eng
Abstract A single-base pair resolution silkworm genetic variation map was constructed from 40 domesticated and wild silkworms, each sequenced to approximately threefold coverage, representing 99.88% of the genome. We identified ∼16 million single-nucleotide polymorphisms, many indels, and structural variations. We find that the domesticated silkworms are clearly genetically differentiated from the wild ones, but they have maintained large levels of genetic variability, suggesting a short domestication event involving a large number of individuals. We also identified signals of selection at 354 candidate genes that may have been important during domestication, some of which have enriched expression in the silk gland, midgut, and testis. These data add to our understanding of the domestication processes and may have applications in devising pest control strategies and advancing the use of silkworms as efficient bioreactors.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
 
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