Melanins and melanogenesis: from pigment cells to human health and technological applications

d'Ischia, Marco, Wakamatsu, Kazumasa, Cicoira, Fabio, Di Mauro, Eduardo, Garcia-Borron, Jose C., Commo, Stephane, Galvan, Ismael, Ghanem, Ghanem, Kenzo, Koike, Meredith, Paul, Pezzella, Alessandro, Santato, Clara, Sarna, Tadeusz, Simon, John D., Zecca, Luigi, Zucca, Fabio A., Napolitano, Alessandra and Ito, Shosuke (2015) Melanins and melanogenesis: from pigment cells to human health and technological applications. Pigment Cell and Melanoma Research, 28 5: 520-544. doi:10.1111/pcmr.12393


Author d'Ischia, Marco
Wakamatsu, Kazumasa
Cicoira, Fabio
Di Mauro, Eduardo
Garcia-Borron, Jose C.
Commo, Stephane
Galvan, Ismael
Ghanem, Ghanem
Kenzo, Koike
Meredith, Paul
Pezzella, Alessandro
Santato, Clara
Sarna, Tadeusz
Simon, John D.
Zecca, Luigi
Zucca, Fabio A.
Napolitano, Alessandra
Ito, Shosuke
Title Melanins and melanogenesis: from pigment cells to human health and technological applications
Journal name Pigment Cell and Melanoma Research   Check publisher's open access policy
ISSN 1755-148X
1755-1471
Publication date 2015-09-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/pcmr.12393
Open Access Status Not Open Access
Volume 28
Issue 5
Start page 520
End page 544
Total pages 25
Place of publication Hoboken, NJ, United States
Publisher Wiley-Blackwell Publishing
Collection year 2016
Language eng
Abstract During the past decade, melanins and melanogenesis have attracted growing interest for a broad range of biomedical and technological applications. The burst of polydopamine-based multifunctional coatings in materials science is just one example, and the list may be expanded to include melanin thin films for organic electronics and bioelectronics, drug delivery systems, functional nanoparticles and biointerfaces, sunscreens, environmental remediation devices. Despite considerable advances, applied research on melanins and melanogenesis is still far from being mature. A closer intersectoral interaction between research centers is essential to raise the interests and increase the awareness of the biomedical, biomaterials science and hi-tech sectors of the manifold opportunities offered by pigment cells and related metabolic pathways. Starting from a survey of biological roles and functions, the present review aims at providing an interdisciplinary perspective of melanin pigments and related pathway with a view to showing how it is possible to translate current knowledge about physical and chemical properties and control mechanisms into new bioinspired solutions for biomedical, dermocosmetic, and technological applications.
Keyword Antioxidants
Bioelectronics
Dermocosmetic applications
Extracutaneous melanins
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Centre for Organic Photonics and Electronics
Official 2016 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 21 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 24 times in Scopus Article | Citations
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