Opioid analgesic agents and cancer cell biology

Xie, Nan and Parat, Marie-Odile (2015) Opioid analgesic agents and cancer cell biology. Current Anesthesiology Reports, 5 3: 278-284. doi:10.1007/s40140-015-0118-5

Author Xie, Nan
Parat, Marie-Odile
Title Opioid analgesic agents and cancer cell biology
Journal name Current Anesthesiology Reports   Check publisher's open access policy
ISSN 2167-6275
Publication date 2015-09-01
Year available 2015
Sub-type Article (original research)
DOI 10.1007/s40140-015-0118-5
Open Access Status Not Open Access
Volume 5
Issue 3
Start page 278
End page 284
Total pages 7
Place of publication Philadelphia, PA United States
Publisher Springer Healthcare
Collection year 2016
Language eng
Abstract There is growing interest in the notion that perioperative factors may influence the long-term outcome of cancer surgery. Among these factors, pharmacologic agents including anesthetics and analgesics have been scrutinized for their potential effect on tumors. Opioids are particularly interesting in this context, as conflicting literature reports both pro- and anti-tumor effects for this class of drugs in every aspect of tumor growth and metastasis that has been examined. Cancer and non-cancer cells important to the tumor biology may be affected, as demonstrated using a variety of in vitro and preclinical models. More evidence is required to optimize the perioperative pain management of cancer surgery patients.
Keyword Cancer cell proliferation
Opioid receptor
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Pharmacy Publications
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Created: Thu, 27 Aug 2015, 15:06:27 EST by Charna Kovacevic on behalf of School of Pharmacy