Late relapses in hodgkin's disease: Are they a distinct entity?

Young, Gar, Perkins, AC, Iland, HJ, Vincent, PC and Kulkarni, A (1991) Late relapses in hodgkin's disease: Are they a distinct entity?. Leukemia and Lymphoma, 4 5-6: 363-369. doi:10.3109/10428199109068087

Author Young, Gar
Perkins, AC
Iland, HJ
Vincent, PC
Kulkarni, A
Title Late relapses in hodgkin's disease: Are they a distinct entity?
Journal name Leukemia and Lymphoma   Check publisher's open access policy
ISSN 1042-8194
Publication date 1991
Sub-type Article (original research)
DOI 10.3109/10428199109068087
Volume 4
Issue 5-6
Start page 363
End page 369
Total pages 7
Publisher Informa Healthcare
Language eng
Subject 2720 Hematology
2730 Oncology
1306 Cancer Research
Abstract It is claimed that late relapses of Hodgkin's disease have a good prognosis when retreated. A number of unfavourable outcomes led us to review our experience of 72 consecutive cases of Hodgkin's disease diagnosed and treated in a combined clinical haematology and radiation oncology unit between 1968 and 1984. 62 of 72 patients (86%) achieved a complete remission and of these, 35 patients (56%) relapsed, 18 occurring more than three years after diagnosis. Thus, 4 patient groups were identified: 10 patients with refractory disease, 27 patients who went into complete remission and have not relapsed, 17 patients who relapsed within 3 years of diagnosis (early relapse) and 18 patients who relapsed more than 3 years from diagnosis (late relapse). Patients who relapsed were retreated with well accepted protocols of chemotherapy and/or radiotherapy with surprisingly poor results. There was no significant difference between the survival from relapse of patients who relapsed early compared to those who relapsed late. Late relapses are not uncommon in Hodgkin's disease and the prognosis may be less favourable than generally perceived. The risk of relapse was almost constant with time and brings into question the concept of early and late relapse.
Keyword Early versus late
Hodgkin's disease
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ResearcherID Downloads
Scopus Import
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 1 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 18 Aug 2015, 11:47:18 EST by System User