Recent developments in capabilities for analysing chlorinated paraffins in environmental matrices: a review

van Mourik, Louise M., Leonards, Pim E. G., Gaus, Caroline and de Boer, Jacob (2015) Recent developments in capabilities for analysing chlorinated paraffins in environmental matrices: a review. Chemosphere, 136 259-272. doi:10.1016/j.chemosphere.2015.05.045


Author van Mourik, Louise M.
Leonards, Pim E. G.
Gaus, Caroline
de Boer, Jacob
Title Recent developments in capabilities for analysing chlorinated paraffins in environmental matrices: a review
Journal name Chemosphere   Check publisher's open access policy
ISSN 0045-6535
1879-1298
Publication date 2015-10
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.chemosphere.2015.05.045
Open Access Status Not yet assessed
Volume 136
Start page 259
End page 272
Total pages 14
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon Press
Collection year 2016
Language eng
Formatted abstract
Concerns about the high production volumes, persistency, bioaccumulation potential and toxicity of chlorinated paraffin (CP) mixtures, especially short-chain CPs (SCCPs), are rising. However, information on their levels and fate in the environment is still insufficient, impeding international classifications and regulations. This knowledge gap is mainly due to the difficulties that arise with CP analysis, in particular the chromatographic separation within CPs and between CPs and other compounds. No fully validated routine analytical method is available yet and only semi-quantitative analysis is possible, although the number of studies reporting new and improved methods have rapidly increased since 2010. Better cleanup procedures that remove interfering compounds, and new instrumental techniques, which distinguish between medium-chain CPs (MCCPs) and SCCPs, have been developed. While gas chromatography coupled to an electron capture negative ionisation mass spectrometry (GC/ECNI-MS) remains the most commonly applied technique, novel and promising use of high resolution time of flight MS (TOF-MS) has also been reported. We expect that recent developments in high resolution TOF-MS and Orbitrap technologies will further improve the detection of CPs, including long-chain CPs (LCCPs), and the group separation and quantification of CP homologues. Also, new CP quantification methods have emerged, including the use of mathematical algorithms, multiple linear regression and principal component analysis. These quantification advancements are also reflected in considerably improved interlaboratory agreements since 2010. Analysis of lower chlorinated paraffins (<Cl5) remains, however, challenging and better approaches to analysing these homologues are needed. Furthermore, suitable quantification standards would facilitate improving the quality of CP analysis.
Keyword Chlorinated paraffin (CP)
Polychlorinated-n-alkane (PCA)
Short-chain chlorinated paraffin (SCCP)
Medium-chain chlorinated paraffin (MCCP)
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
National Research Centre for Environmental Toxicology Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 10 times in Thomson Reuters Web of Science Article | Citations
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