The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A (H7N9): a cross-sectional observational study in four eastern China provinces

Zhou, Xiaoyan, Li, Yin, Wang, Youming, Edwards, John, Guo, Fusheng, Clements, Archie C. A., Huang, Baoxu and Soares Magalhaes, Ricardo J. (2015) The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A (H7N9): a cross-sectional observational study in four eastern China provinces. Journal of Infection, 71 4: 470-479. doi:10.1016/j.jinf.2015.06.012


Author Zhou, Xiaoyan
Li, Yin
Wang, Youming
Edwards, John
Guo, Fusheng
Clements, Archie C. A.
Huang, Baoxu
Soares Magalhaes, Ricardo J.
Title The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A (H7N9): a cross-sectional observational study in four eastern China provinces
Journal name Journal of Infection   Check publisher's open access policy
ISSN 1532-2742
0163-4453
Publication date 2015-07-03
Sub-type Article (original research)
DOI 10.1016/j.jinf.2015.06.012
Open Access Status DOI
Volume 71
Issue 4
Start page 470
End page 479
Total pages 10
Place of publication London, United Kingdom
Publisher W.B. Saunders (Elsevier)
Collection year 2016
Language eng
Formatted abstract
Background:  A new reassortant influenza A (H7N9) virus emerged early 2013 in eastern China. Exposure to H7N9 infected poultry at live bird markets (LBM) was implicated as the main risk factor for human infection. We aimed to identify the role of LBM biosecurity indicators and poultry movement in the affected areas.

Methods:  A cross-sectional survey was carried out in 24 LBMs at the beginning of H7N9 outbreak in all affected provinces. We used univariable analysis to identify the biosecurity factors associated with the H7N9 presence in LBMs and social network and spatial analysis to quantify the connectivity and geographic variation in the connectivity of poultry movements.

Results:  Chickens were the predominant poultry species traded by affected LBMs. The presence of H7N9 in LBMs was significantly associated with the type of LBM and with LBMs that sold chicken to other markets. The chicken movements were significantly spatially clustered and was highest in counties from Jiangsu and Anhui provinces.

Conclusion:  LBM biosecurity and chicken movement played an important role in the emergence of H7N9. This study identified highly connected areas in eastern China which continue to report human infections highlighting candidate areas for more detailed epidemiological investigations.
Keyword Influenza A (H7N9)
Poultry movement
Live bird markets
Meat chicken
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article in press corrected proof.

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 5 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 28 Jul 2015, 02:20:41 EST by System User on behalf of Scholarly Communication and Digitisation Service