Associations of sedentary time patterns and TV viewing time with inflammatory and endothelial function biomarkers in children

Gabel, L., Ridgers, N. D., Della Gatta, P. A., Arundell, L., Cerin, E., Robinson, S., Daly, R. M., Dunstan, D. W. and Salmon, J. (2015) Associations of sedentary time patterns and TV viewing time with inflammatory and endothelial function biomarkers in children. Pediatric Obesity, 1-8. doi:10.1111/ijpo.12045


Author Gabel, L.
Ridgers, N. D.
Della Gatta, P. A.
Arundell, L.
Cerin, E.
Robinson, S.
Daly, R. M.
Dunstan, D. W.
Salmon, J.
Title Associations of sedentary time patterns and TV viewing time with inflammatory and endothelial function biomarkers in children
Journal name Pediatric Obesity   Check publisher's open access policy
ISSN 2047-6310
2047-6302
Publication date 2015-06-19
Sub-type Article (original research)
DOI 10.1111/ijpo.12045
Start page 1
End page 8
Total pages 8
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2016
Language eng
Formatted abstract
Objective: Investigate associations of TV viewing time and accelerometry-derived sedentary time with inflammatory and endothelial function biomarkers in children.
Methods: Cross-sectional analysis of 164 7–10-year-old children. TV viewing time was assessed by parental proxy report and total and patterns of sedentary time accumulation (e.g. prolonged bouts) were assessed by accelerometry. C-reactive protein (CRP), homeostasis model assessment of insulin resistance, interleukin-2, -6, -8, -10, tumour necrosis factor alpha, adiponectin, resistin, brain-derived neurotrophic factor, soluble intercellular and vascular adhesion molecule 1, plasminogen activator inhibitor 1 and soluble E-selectin were assessed. Generalised linear models assessed the associations of TV viewing and sedentary time with biomarkers, adjusting for sex, waist circumference, moderate- to vigorous-intensity physical activity and diet density.
Results: Each additional h week−1 of TV viewing was associated with 4.4% (95% CI: 2.1, 6.7) greater CRP and 0.6% (0.2, 1.0) greater sVCAM-1 in the fully adjusted model. The association between frequency and duration of 5–10 min bouts of sedentary time and CRP was positive after adjustment for sex and waist circumference but attenuated after adjustment for diet density.
Conclusions: This study suggests that TV viewing was unfavourably associated with several markers of inflammation and endothelial dysfunction. The detrimental association between 5 and 10 min bouts of sedentary time and CRP approached significance, suggesting that further research with a stronger study design (longitudinal and/or experimental) is needed to better understand how the accumulation of sedentary time early in life may influence short and longer term health.
Keyword Cardiometabolic
Paediatric
Sedentary behaviour
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Early view of article.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Public Health Publications
 
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