Changes in the Relationships Between Body Mass Index and Health Outcomes Across Middle Age and Older Adulthood

Peeters, G. M. E. E.(Geeske), Herber-Gast, Gerrie-Cor M., Dobson, Annette J. and Brown, Wendy J. (2015) Changes in the Relationships Between Body Mass Index and Health Outcomes Across Middle Age and Older Adulthood. Mayo Clinic Proceedings, 90 7: 903-910. doi:10.1016/j.mayocp.2015.04.006


Author Peeters, G. M. E. E.(Geeske)
Herber-Gast, Gerrie-Cor M.
Dobson, Annette J.
Brown, Wendy J.
Title Changes in the Relationships Between Body Mass Index and Health Outcomes Across Middle Age and Older Adulthood
Journal name Mayo Clinic Proceedings   Check publisher's open access policy
ISSN 0025-6196
1942-5546
Publication date 2015-07
Year available 2015
Sub-type Article (original research)
DOI 10.1016/j.mayocp.2015.04.006
Open Access Status
Volume 90
Issue 7
Start page 903
End page 910
Total pages 8
Place of publication New York, NY United States
Publisher Elsevier
Collection year 2016
Language eng
Formatted abstract
Objective: To examine patterns of the incidence of diabetes, hypertension, and mortality by single units of body mass index (BMI) and 5-year age groups using longitudinal data from middle-aged and older women.

Patients and Methods: Middle-aged (born between 1946 and 1951; N=13,715) and older (born between 1921 and 1926; N=12,432) participants in the Australian Longitudinal Study on Women's Health completed surveys in 1996 and at approximately 3-year intervals thereafter until 2011. Proportions of women with diabetes, hypertension, and mortality over 3-year intervals were estimated for each unit of BMI and 5-year age group (45 to <50, 50 to <55, 55 to <60, 70 to <75, 75 to <80, and 80 to <85 years) using generalized additive modeling with adjustment for time-varying covariates.

Results: Three-year incidence of diabetes (1.2%-3.6%), hypertension (5.2%-17.8%), and death (0.4%-9.5%) increased with age. For both diabetes and hypertension, the associations with BMI were curvilinear in middle-aged women and became almost linear in older women. With increasing age, the slope became steeper, and the increase started at lower BMI values. For hypertension, there was a marked increase in intercept from 75 years onward. In contrast, mortality risks were highest for low BMI (≤20) in all age groups. A clear U-shaped curve was observed only in the oldest age group.

Conclusion: The shapes of the relationships between BMI and incidence of diabetes, hypertension, and mortality change with age, suggesting that weight management interventions should be tailored for different age groups.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Public Health Publications
School of Human Movement and Nutrition Sciences Publications
 
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Created: Fri, 03 Jul 2015, 11:21:18 EST by Sandrine Ducrot on behalf of School of Human Movement and Nutrition Sciences