Interactions between chitosan and alginate dialdehyde biopolymers and their layer-by-layer assemblies

Aston, Robyn, Wimalaratne, Medini, Brock, Aidan, Lawrie, Gwendolyn and Grondahl, Lisbeth (2015) Interactions between chitosan and alginate dialdehyde biopolymers and their layer-by-layer assemblies. Biomacromolecules, 16 6: 1807-1817. doi:10.1021/acs.biomac.5b00383


Author Aston, Robyn
Wimalaratne, Medini
Brock, Aidan
Lawrie, Gwendolyn
Grondahl, Lisbeth
Title Interactions between chitosan and alginate dialdehyde biopolymers and their layer-by-layer assemblies
Journal name Biomacromolecules   Check publisher's open access policy
ISSN 1526-4602
1525-7797
Publication date 2015-06-08
Year available 2015
Sub-type Article (original research)
DOI 10.1021/acs.biomac.5b00383
Open Access Status
Volume 16
Issue 6
Start page 1807
End page 1817
Total pages 11
Place of publication Washington, DC United States
Publisher American Chemical Society
Collection year 2016
Language eng
Formatted abstract
Biopolymers are researched extensively for their applications in biomaterials science and drug delivery including structures and complexes of more than one polymer. Chemical characterization of complexes formed between chitosan (CHI) and alginate dialdehyde (ADA) biopolymers established that while electrostatic interactions dominate (as determined from X-ray photoelectron spectroscopy (XPS)) covalent cross-linking between these biopolymers also contribute to their stability (evidenced from immersion in salt solution). It was furthermore found that imine bond formation could not be directly detected by any of the techniques XPS, FTIR, 1H NMR, or fluorescence. The layer-by-layer assemblies of the biopolymers formed on silica colloids, glass slides, and alginate hydrogel beads were evaluated using XPS, as well as zeta potential measurements for the silica colloids and changes to hydration properties for the hydrogels. It was found that the degree of oxidation of ADA affected the LbL assemblies in terms of a greater degree of CHI penetration observed when using the more conformationally flexible biopolymer ADA (higher degree of oxidation).
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
 
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