Host-pathogen interaction during bacterial vaccination

Barnett, Timothy C., Lim, Jin Yan, Soderholm, Amelia T., Rivera-Hernandez, Tania, West, Nicholas P. and Walker, Mark J. (2015) Host-pathogen interaction during bacterial vaccination. Current Opinion in Immunology, 36 1-7. doi:10.1016/j.coi.2015.04.002

Author Barnett, Timothy C.
Lim, Jin Yan
Soderholm, Amelia T.
Rivera-Hernandez, Tania
West, Nicholas P.
Walker, Mark J.
Title Host-pathogen interaction during bacterial vaccination
Journal name Current Opinion in Immunology   Check publisher's open access policy
ISSN 1879-0372
Publication date 2015-10-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.coi.2015.04.002
Open Access Status
Volume 36
Start page 1
End page 7
Total pages 7
Place of publication Kidlington, Oxford, United Kingdom
Publisher Elsevier
Collection year 2016
Language eng
Abstract Vaccines have been developed and deployed against several important bacterial pathogens of humans, including Neisseria meningitidis, Bordetella pertussis, Streptococcus pneumoniae and Mycobacterium tuberculosis. These vaccines are generally considered a successful public health measure and are effective at controlling disease symptoms and/or burden. However, a troubling consequence of recent vaccination programs has been the selection of vaccine escape mutants, whereby the pathogen displays a different repertoire of immune targets than those represented in the vaccine formulation. To address these issues of antigenic variation and bacterial evolution, continued and sustained efforts in epidemiological surveillance, vaccine development/formulation research, and understanding of the host-pathogen interaction are required.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 3 times in Scopus Article | Citations
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Created: Fri, 19 Jun 2015, 11:40:11 EST by Anthony Yeates on behalf of School of Chemistry & Molecular Biosciences