Inheritance and Characterization of Strong Resistance to Phosphine in Sitophilus oryzae (L.)

Nguyen, Tam T., Collins, Patrick J. and Ebert, Paul R. (2015) Inheritance and Characterization of Strong Resistance to Phosphine in Sitophilus oryzae (L.). PLoS One, 10 4: . doi:10.1371/journal.pone.0124335

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Author Nguyen, Tam T.
Collins, Patrick J.
Ebert, Paul R.
Title Inheritance and Characterization of Strong Resistance to Phosphine in Sitophilus oryzae (L.)
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2015-04
Sub-type Article (original research)
DOI 10.1371/journal.pone.0124335
Open Access Status DOI
Volume 10
Issue 4
Total pages 14
Place of publication San Francisco, CA United States
Publisher Public Library of Science
Collection year 2016
Language eng
Formatted abstract
Sitophilus oryzae (Linnaeus) is a major pest of stored grain across Southeast Asia and is of increasing concern in other regions due to the advent of strong resistance to phosphine, the fumigant used to protect stored grain from pest insects. We investigated the inheritance of genes controlling resistance to phosphine in a strongly resistant S. oryzae strain (NNSO7525) collected in Australia and find that the trait is autosomally inherited and incompletely recessive with a degree of dominance of -0.66. The strongly resistant strain has an LC50 52 times greater than a susceptible reference strain (LS2) and 9 times greater than a weakly resistant strain (QSO335). Analysis of F2 and backcross progeny indicates that two or more genes are responsible for strong resistance, and that one of these genes, designated So_rph1, not only contributes to strong resistance, but is also responsible for the weak resistance phenotype of strain QSO335. These results demonstrate that the genetic mechanism of phosphine resistance in S. oryzae is similar to that of other stored product insect pests. A unique observation is that a subset of the progeny of an F1 backcross generation are more strongly resistant to phosphine than the parental strongly resistant strain, which may be caused by multiple alleles of one of the resistance genes.
Keyword Pesticide Resistance
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Biological Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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