Risk factors for deterioration of renal function after coronary artery bypass grafting

van Straten, Albert H. M., Hamad, Mohamed A. Soliman, van Zundert, Andre A. A. J., Martens, Elisabeth J., Schonberger, Jacques P. A. M. and de Wolf, Andre M. (2010) Risk factors for deterioration of renal function after coronary artery bypass grafting. European Journal of Cardio-thoracic Surgery, 37 1: 106-111. doi:10.1016/j.ejcts.2009.06.048


Author van Straten, Albert H. M.
Hamad, Mohamed A. Soliman
van Zundert, Andre A. A. J.
Martens, Elisabeth J.
Schonberger, Jacques P. A. M.
de Wolf, Andre M.
Title Risk factors for deterioration of renal function after coronary artery bypass grafting
Journal name European Journal of Cardio-thoracic Surgery   Check publisher's open access policy
ISSN 1010-7940
1873-734X
Publication date 2010
Year available 2010
Sub-type Article (original research)
DOI 10.1016/j.ejcts.2009.06.048
Open Access Status
Volume 37
Issue 1
Start page 106
End page 111
Total pages 6
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Abstract Objective: Various definitions of impairment of renal function after coronary artery bypass grafting (CABG) are used in the literature. Depending on the definition, several risk factors are identified. We analysed our data to determine the risk factors for postoperative deterioration of the creatinine clearance of 10% or more. Methods: All patients undergoing isolated coronary surgery in a single centre between January 1998 and December 2007 are included. Clinical data, including demographics and renal risk factors, were prospectively collected in our database. The most recent preoperative serum creatinine level and the maximum serum creatinine level within the first week postoperatively were used to calculate the creatinine clearance. A deterioration of 10% or more was considered to be an endpoint for this study. Results: In 10 098 out of a total of 10 626 patients, the preoperative as well as the postoperative creatinine clearance could be calculated. In 1053 patients, the deterioration of the creatinine clearance was 10% or more. We could identify the following risk factors: advanced age, diabetes, chronic obstructive pulmonary disease, peripheral vascular disease, emergency operation, previous cardiac surgery, low preoperative haemoglobin level, high preoperative C-reactive protein level, perioperative myocardial infarction, re-exploration and the number of blood transfusions. Conclusions: Risk factors for the deterioration of renal function after revascularisation have been confirmed in this study. In addition, we found peripheral vascular disease, previous cardiac surgery, low preoperative haemoglobin, increased preoperative C-reactive protein level, perioperative myocardial infarction and the number of blood transfusions to be risk factors that have not been described earlier.
Keyword CABG
Coronary artery bypass grafting
Database
Renal function
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 20 May 2015, 15:37:15 EST by Andre Van Zundert on behalf of Anaesthesiology and Critical Care - RBWH