Electrospinning of silk nanofibers. I. An investigation of nanofiber morphology and process optimization using response surface methodology

Amiraliyan, Nasim, Nouri, Mahdi and Kish, Mohammad Haghighat (2009) Electrospinning of silk nanofibers. I. An investigation of nanofiber morphology and process optimization using response surface methodology. Fibers and Polymers, 10 2: 167-176. doi:10.1007/s12221-009-0167-9


Author Amiraliyan, Nasim
Nouri, Mahdi
Kish, Mohammad Haghighat
Title Electrospinning of silk nanofibers. I. An investigation of nanofiber morphology and process optimization using response surface methodology
Journal name Fibers and Polymers   Check publisher's open access policy
ISSN 1229-9197
Publication date 2009
Sub-type Article (original research)
DOI 10.1007/s12221-009-0167-9
Open Access Status
Volume 10
Issue 2
Start page 167
End page 176
Total pages 10
Place of publication Dordrecht, Netherlands
Publisher Springer Netherlands
Subject 1500 Chemical Engineering
1600 Chemistry
2507 Polymers and Plastics
Abstract Ultra fine fibers were electrospun from regenerated silk fibroin/formic acid solution. Effect of some process parameters on the morphology, diameter and variation in fiber diameter of electrospun fibers were experimentally investigated. Scanning electron microscope was used for the measurement of fiber diameter. Fibers with diameter ranging from 80 to 210 nm were collected depending on the solution concentration and the applied voltages. Response surface methodology (RSM) was used to obtain a quantitative relationship between selected electrospinning parameters and the average fiber diameters and its distribution. It was shown that concentration of silk fibroin solution had a significant effect on the fiber diameter and the standard deviation of the fiber diameter. Applied voltage had no significant effect on the fiber diameter and its standard deviation.
Keyword Biopolymer
Electron microscopy
Morphology
Nanofiber
Protein
Statistical analysis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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