Isolation of Nocardia mexicana from focal proliferative tenosynovitis and arthritis in a steer

Owen, H., Buckle, K., Olm, J., Leitner, M., Pandey, S., Gaughan, J. B., Sullivan, M. L., Lees, A. M. and Gibson, J. S. (2015) Isolation of Nocardia mexicana from focal proliferative tenosynovitis and arthritis in a steer. Australian Veterinary Journal, 93 5: 170-173. doi:10.1111/avj.12308


Author Owen, H.
Buckle, K.
Olm, J.
Leitner, M.
Pandey, S.
Gaughan, J. B.
Sullivan, M. L.
Lees, A. M.
Gibson, J. S.
Title Isolation of Nocardia mexicana from focal proliferative tenosynovitis and arthritis in a steer
Formatted title
Isolation of Nocardia mexicana from focal proliferative tenosynovitis and arthritis in a steer
Journal name Australian Veterinary Journal   Check publisher's open access policy
ISSN 1751-0813
0005-0423
Publication date 2015-05-01
Year available 2015
Sub-type Article (original research)
DOI 10.1111/avj.12308
Open Access Status
Volume 93
Issue 5
Start page 170
End page 173
Total pages 4
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2016
Language eng
Formatted abstract
Case report

An 18-month-old Charolais steer was presented with lameness and fluctuant swelling of the right stifle joint, which yielded neutrophils on fine-needle aspiration. A diagnosis of bacterial proliferative tenosynovitis and arthritis was made on postmortem and histological examination. Culture and 16S rRNA sequencing identified a Nocardia sp. with 99% homology with the corresponding DNA fragment of N. mexicana DSM 44952. Antimicrobial susceptibility testing revealed the isolate was susceptible to co-trimoxazole and third-generation cephalosporins.

Conclusion

We report the first case, both in Australia and internationally, of proliferative tenosynovitis and arthritis caused by Nocardia spp. infection in a bovine and the first report of pathology attributed to N. mexicana in a veterinary patient. Given the limited susceptibility of the bacteria, the poor antimicrobial penetration that would be expected and the morphological changes that had taken place in the joint; the steer would have required protracted antimicrobial treatment in addition to invasive debridement of the lesion. This case emphasises the importance of routinely performing cytology and extended incubation of cultures in cases of arthritis in order to make ethical and economically viable treatment decisions.
Keyword Arthritis
Cattle
Nocardia mexicana
Proliferative tenosynovitis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Agriculture and Food Sciences
Official 2016 Collection
School of Veterinary Science Publications
 
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