Review: environmental mycobacteria as a cause of human infection

Halstrom, Samuel, Price, Patricia and Thomson, Rachel (2015) Review: environmental mycobacteria as a cause of human infection. International Journal of Mycobacteriology, 4 2: 81-91. doi:10.1016/j.ijmyco.2015.03.002

Author Halstrom, Samuel
Price, Patricia
Thomson, Rachel
Title Review: environmental mycobacteria as a cause of human infection
Journal name International Journal of Mycobacteriology   Check publisher's open access policy
ISSN 2212-554X
Publication date 2015-06
Year available 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.ijmyco.2015.03.002
Open Access Status DOI
Volume 4
Issue 2
Start page 81
End page 91
Total pages 10
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Collection year 2016
Abstract Pulmonary infections with nontuberculous mycobacteria (NTM) are recognized as a problem in immunodeficient individuals and are increasingly common in older people with no known immune defects. NTM are found in soil and water, but factors influencing transmission from the environment to humans are mostly unknown. Studies of the epidemiology of NTM disease have matched some clinical isolates of NTM with isolates from the patient's local environment. Definitive matching requires strain level differentiation based on molecular analyses, including partial sequencing, PCR-restriction fragment length polymorphism (RFLP) analysis, random amplified polymorphic DNA (RAPD) PCR, repetitive element (rep-) PCR and pulsed field gel electrophoresis (PFGE) of large restriction fragments. These approaches have identified hospital and residential showers and faucets, hot-tubs and garden soil as sources of transmissible pathogenic NTM. However, gaps exist in the literatscure, with many clinical isolates remaining unidentified within environments that have been tested, and few studies investigating NTM transmission in developing countries. To understand the environmental reservoirs and transmission routes of pathogenic NTM, different environments, countries and climates must be investigated.
Keyword Dust
Nontuberculous mycobacteria
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Medicine Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 05 May 2015, 01:07:11 EST by System User on behalf of Scholarly Communication and Digitisation Service