Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure

Rateesh, Shruti, Shekar, Kiran, Naidoo, Rishendran, Mittal, Dolly and Bhaskar, Balu (2015) Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure. Circulation: Heart Failure, 8 2: 381-383. doi:10.1161/CIRCHEARTFAILURE.115.002080


Author Rateesh, Shruti
Shekar, Kiran
Naidoo, Rishendran
Mittal, Dolly
Bhaskar, Balu
Title Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure
Journal name Circulation: Heart Failure   Check publisher's open access policy
ISSN 1941-3289
1941-3297
Publication date 2015-03
Sub-type Editorial
DOI 10.1161/CIRCHEARTFAILURE.115.002080
Open Access Status
Volume 8
Issue 2
Start page 381
End page 383
Total pages 3
Place of publication Philadelphia PA, United States
Publisher Lippincott Williams & Wilkins
Collection year 2016
Language eng
Abstract Extracorporeal life support has evolved to become a viable support option in patients with acute cardiac failure. Tailored mechanical circulatory support (MCS) can now be provided to patients using existing extracorporeal life support devices. We report the successful use of peripheral venoarterial extracorporeal membrane oxygenation (ECMO) to provide MCS to a patient with acute 5-flurouracil (5-FU)–induced cardiomyopathy. 5-FU is a key component of adjuvant chemotherapy for colorectal cancer. It is also frequently used in the treatment of gastric, esophageal, pancreatic, breast, bladder, and prostate cancer. There is a wide range of cardiotoxicity with this 5-FU, including ischemia, vasospasm, arrhythmia, hypertension, Q-T interval prolongation, and acute cardiomyopathy and 5-FU–induced cardiac complications are not rare. This case illustrates the crucial place of ECMO as a bridge to recovery in chemotherapy, cardiomyopathy, or decision making.
Keyword Acute heart failure
Drug-related side effects and adverse reactions
Extracorporeal life support
Extracorporeal membrane oxygenation support
Shock, cardiogenic
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Editorial
Collections: Non HERDC
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Sun, 03 May 2015, 00:31:13 EST by System User on behalf of School of Medicine