A retrospective study of Babesia macropus associated with morbidity and mortality in eastern grey kangaroos (Macropus giganteus) and agile wallabies (Macropus agilis)

Donahoe, Shannon L, Peacock, Christopher S, Choo, Ace Y. L, Cook, Roger W, O'Donoghue, Peter, Crameri, Sandra, Vogelnest, Larry, Gordon, Anita N, Scott, Jenni L and Rose, Karrie (2015) A retrospective study of Babesia macropus associated with morbidity and mortality in eastern grey kangaroos (Macropus giganteus) and agile wallabies (Macropus agilis). International Journal for Parasitology: Parasites and Wildlife, 4 2: 268-276. doi:10.1016/j.ijppaw.2015.02.002


Author Donahoe, Shannon L
Peacock, Christopher S
Choo, Ace Y. L
Cook, Roger W
O'Donoghue, Peter
Crameri, Sandra
Vogelnest, Larry
Gordon, Anita N
Scott, Jenni L
Rose, Karrie
Title A retrospective study of Babesia macropus associated with morbidity and mortality in eastern grey kangaroos (Macropus giganteus) and agile wallabies (Macropus agilis)
Journal name International Journal for Parasitology: Parasites and Wildlife   Check publisher's open access policy
ISSN 2213-2244
Publication date 2015-08
Year available 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.ijppaw.2015.02.002
Open Access Status DOI
Volume 4
Issue 2
Start page 268
End page 276
Total pages 9
Place of publication Langford Lane, United Kingdom
Publisher Australian Society for Parasitology (Elsevier)
Collection year 2016
Language eng
Formatted abstract
This is a retrospective study of 38 cases of infection by Babesia macropus, associated with a syndrome of anaemia and debility in hand-reared or free-ranging juvenile eastern grey kangaroos (Macropus giganteus) from coastal New South Wales and south-eastern Queensland between 1995 and 2013. Infection with B. macropus is recorded for the first time in agile wallabies (Macropus agilis) from far north Queensland. Animals in which B. macropus infection was considered to be the primary cause of morbidity had marked anaemia, lethargy and neurological signs, and often died. In these cases, parasitised erythrocytes were few or undetectable in peripheral blood samples but were sequestered in large numbers within small vessels of visceral organs, particularly in the kidney and brain, associated with distinctive clusters of extraerythrocytic organisms. Initial identification of this piroplasm in peripheral blood smears and in tissue impression smears and histological sections was confirmed using transmission electron microscopy and molecular analysis. Samples of kidney, brain or blood were tested using PCR and DNA sequencing of the 18S ribosomal RNA and heat shock protein 70 gene using primers specific for piroplasms. The piroplasm detected in these samples had 100% sequence identity in the 18S rRNA region with the recently described Babesia macropus in two eastern grey kangaroos from New South Wales and Queensland, and a high degree of similarity to an unnamed Babesia sp. recently detected in three woylies (Bettongia penicillata ogilbyi) in Western Australia.
Keyword Babesia
Piroplasm
Anaemia
Kangaroo
Wallaby
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 2 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 21 Apr 2015, 04:49:23 EST by System User on behalf of Scholarly Communication and Digitisation Service