Tourette syndrome deep brain stimulation: A review and updated recommendations

Schrock, Lauren E, Mink, Jonathan W, Woods, Douglas W, Porta, Mauro, Servello, Dominico, Visser-Vandewalle, Veerle, Silburn, Peter A, Foltynie, Thomas, Walker, Harrison C, Shahed-Jimenez, Joohi, Savica, Rodolfo, Klassen, Bryan T, Machado, Andre G, Foote, Kelly D, Zhang, Jian-Guo, Hu, Wei, Ackermans, Linda, Temel, Yasin, Mari, Zoltan, Changizi, Barbara K, Lozano, Andres, Auyeung, M, Kaido, Takanobu, Agid, Yves, Welter, Marie L, Khandhar, Suketu M, Mogilner, Alon Y, Pourfar, Michael H, Walter, Benjamin L, Juncos, Jorge L, Gross, Robert E, Kuhn, Jens, Leckman, James F, Neimat, Joseph A and Okun, Michael S (2015) Tourette syndrome deep brain stimulation: A review and updated recommendations. Movement Disorders, 30 4: 448-471. doi:10.1002/mds.26094

Author Schrock, Lauren E
Mink, Jonathan W
Woods, Douglas W
Porta, Mauro
Servello, Dominico
Visser-Vandewalle, Veerle
Silburn, Peter A
Foltynie, Thomas
Walker, Harrison C
Shahed-Jimenez, Joohi
Savica, Rodolfo
Klassen, Bryan T
Machado, Andre G
Foote, Kelly D
Zhang, Jian-Guo
Hu, Wei
Ackermans, Linda
Temel, Yasin
Mari, Zoltan
Changizi, Barbara K
Lozano, Andres
Auyeung, M
Kaido, Takanobu
Agid, Yves
Welter, Marie L
Khandhar, Suketu M
Mogilner, Alon Y
Pourfar, Michael H
Walter, Benjamin L
Juncos, Jorge L
Gross, Robert E
Kuhn, Jens
Leckman, James F
Neimat, Joseph A
Okun, Michael S
Title Tourette syndrome deep brain stimulation: A review and updated recommendations
Journal name Movement Disorders   Check publisher's open access policy
ISSN 1531-8257
Publication date 2015-04
Year available 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/mds.26094
Volume 30
Issue 4
Start page 448
End page 471
Total pages 24
Place of publication Hoboken, United States
Publisher John Wiley & Sons, Inc
Collection year 2016
Language eng
Abstract Deep brain stimulation (DBS) may improve disabling tics in severely affected medication and behaviorally resistant Tourette syndrome (TS). Here we review all reported cases of TS DBS and provide updated recommendations for selection, assessment, and management of potential TS DBS cases based on the literature and implantation experience. Candidates should have a Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM V) diagnosis of TS with severe motor and vocal tics, which despite exhaustive medical and behavioral treatment trials result in significant impairment. Deep brain stimulation should be offered to patients only by experienced DBS centers after evaluation by a multidisciplinary team. Rigorous preoperative and postoperative outcome measures of tics and associated comorbidities should be used. Tics and comorbid neuropsychiatric conditions should be optimally treated per current expert standards, and tics should be the major cause of disability. Psychogenic tics, embellishment, and malingering should be recognized and addressed. We have removed the previously suggested 25-year-old age limit, with the specification that a multidisciplinary team approach for screening is employed. A local ethics committee or institutional review board should be consulted for consideration of cases involving persons younger than 18 years of age, as well as in cases with urgent indications. Tourette syndrome patients represent a unique and complex population, and studies reveal a higher risk for post-DBS complications. Successes and failures have been reported for multiple brain targets; however, the optimal surgical approach remains unknown. Tourette syndrome DBS, though still evolving, is a promising approach for a subset of medication refractory and severely affected patients
Keyword Tourette syndrome
Deep brain stimulation
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2016 Collection
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Citation counts: TR Web of Science Citation Count  Cited 40 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 32 times in Scopus Article | Citations
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