Incidental gonadal tumors at the time of gonadectomy in women with Swyer syndrome: a case series

Hanlon, Amie J. M. and Kimble, Rebecca M. (2015) Incidental gonadal tumors at the time of gonadectomy in women with Swyer syndrome: a case series. Journal of Pediatric and Adolescent Gynecology, 28 2: e27-e29. doi:10.1016/j.jpag.2014.07.017

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Author Hanlon, Amie J. M.
Kimble, Rebecca M.
Title Incidental gonadal tumors at the time of gonadectomy in women with Swyer syndrome: a case series
Journal name Journal of Pediatric and Adolescent Gynecology   Check publisher's open access policy
ISSN 1873-4332
1083-3188
Publication date 2015-04-01
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.jpag.2014.07.017
Open Access Status
Volume 28
Issue 2
Start page e27
End page e29
Total pages 3
Place of publication Philadelphia, PA United States
Publisher Elsevier
Collection year 2015
Language eng
Formatted abstract
Background

Swyer syndrome (46XY complete gonadal dysgenesis) is an uncommonly encountered condition in our population. Gonadectomy is recommended upon diagnosis due to a significant risk of malignant transformation of the dysgenetic gonads, typically to dysgerminoma.

Cases

We present 3 cases of women who underwent gonadectomy following a diagnosis of Swyer syndrome. Two of these patients had dysgerminoma confirmed on histopathology. In particular we discuss the macroscopic appearance of the affected gonads and the further management of each case.

Summary and Conclusion

Individuals with Swyer syndrome require gonadectomy upon diagnosis of their condition, as part of their multidisciplinary management. For treatment of early stage dysgerminoma, surgical resection of the involved gonad and fallopian tube is curative, again highlighting the need for early intervention.
Keyword Gonadal dysgenesis
46 XY
Gonadoblastoma
Dysgerminoma
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 12 August 2014

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
 
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