Future directions in genetics of psychiatric disorders

Wray, Naomi R., Byrne, Enda M., Stringer, Sven and Mowry, Bryan J. (2014). Future directions in genetics of psychiatric disorders. In Behavior genetics of psychopathology (pp. 311-337) New York, NY, United States: Springer New York. doi:10.1007/978-1-4614-9509-3_11


Author Wray, Naomi R.
Byrne, Enda M.
Stringer, Sven
Mowry, Bryan J.
Title of chapter Future directions in genetics of psychiatric disorders
Title of book Behavior genetics of psychopathology
Place of Publication New York, NY, United States
Publisher Springer New York
Publication Year 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/978-1-4614-9509-3_11
Open Access Status
Year available 2014
Series Advances in behavior genetics
ISBN 9781461495086
9781461495093
Volume number 2
Chapter number 11
Start page 311
End page 337
Total pages 27
Total chapters 11
Collection year 2015
Language eng
Abstract/Summary From the view of statistical genetics, we explore four future directions in the genetics of psychiatric disorders with the overall goal of application to genomic medicine. The themes are (1) defining genomic variation, (2) response to treatment genomics, (3) genetic risk prediction and (4) data collection for individuals measured for phenotype, genotype and environment. We conclude that genotyping technology is no longer a limiting step and that full progression of applications of genomic medicine in psychiatry is dependent on the availability of suitable individual level data and will ultimately depend on integration of genomic information as part of accessible electronic health records.
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes This work was funded by grants from the Australian Research Council (FT0911360) and the Australian National Health and Medical Research Council (613608, 1011506).

 
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Created: Mon, 20 Apr 2015, 15:47:05 EST by Caitlin Maskell on behalf of Queensland Brain Institute