Obesity paradox in different populations: Evidence and controversies

Goel K., Lopez-Jimenez F., De Schutter A., Coutinho T. and Lavie C.J. (2014) Obesity paradox in different populations: Evidence and controversies. Future Cardiology, 10 1: 81-91. doi:10.2217/fca.13.84


Author Goel K.
Lopez-Jimenez F.
De Schutter A.
Coutinho T.
Lavie C.J.
Title Obesity paradox in different populations: Evidence and controversies
Journal name Future Cardiology   Check publisher's open access policy
ISSN 1479-6678
1744-8298
Publication date 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2217/fca.13.84
Open Access Status
Volume 10
Issue 1
Start page 81
End page 91
Total pages 11
Place of publication London, England, U.K.
Publisher Future Medicine Ltd.
Collection year 2015
Language eng
Subject 2705 Cardiology and Cardiovascular Medicine
1313 Molecular Medicine
Abstract An inverse association between BMI and mortality has been reported in patients with coronary heart disease and heart failure. This 'obesity paradox' has recently been reported in other disease states, including stroke, hypertension, incident diabetes, atrial fibrillation, hemodialysis and transcatheter aortic valve replacement. Cardiorespiratory fitness influences the obesity paradox and this inverse association may be present only in individuals with low fitness levels. Intentional weight loss, exercise training and improving lean mass are important and should be advised to all patients. Recent studies have also explored the association between measures of central obesity and direct measures of body fat with mortality. This review will summarize the evidence, controversies and mechanisms associated with the puzzling obesity paradox.
Keyword body fat
cardiorespiratory fitness
central obesity
coronary heart disease
fitness
heart failure
mortality
obesity paradox
other populations
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Medicine Publications
 
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Created: Wed, 08 Apr 2015, 13:03:56 EST by Matthew Lamb on behalf of School of Medicine