Optimal aspirin dose in acute coronary syndromes: An emerging consensus

Dinicolantonio J.J., Norgard N.B., Meier P., Lavie C.J., O'Keefe J.H., Niazi A.K., Chatterjee S., Packard K.A., D'Ascenzo F., Cerrato E., Biondi-Zoccai G., Bangalore S., Fuchs F.D. and Serebruany V.L. (2014) Optimal aspirin dose in acute coronary syndromes: An emerging consensus. Future Cardiology, 10 2: 291-300. doi:10.2217/fca.14.7


Author Dinicolantonio J.J.
Norgard N.B.
Meier P.
Lavie C.J.
O'Keefe J.H.
Niazi A.K.
Chatterjee S.
Packard K.A.
D'Ascenzo F.
Cerrato E.
Biondi-Zoccai G.
Bangalore S.
Fuchs F.D.
Serebruany V.L.
Title Optimal aspirin dose in acute coronary syndromes: An emerging consensus
Journal name Future Cardiology   Check publisher's open access policy
ISSN 1744-8298
Publication date 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2217/fca.14.7
Open Access Status
Volume 10
Issue 2
Start page 291
End page 300
Total pages 10
Publisher Future Medicine Ltd.
Subject 2705 Cardiology and Cardiovascular Medicine
1313 Molecular Medicine
2700 Medicine
Abstract Numerous clinical trials testing the efficacy of aspirin for the secondary prevention of cardiovascular disease have been published. We reviewed the literature pertaining to aspirin dose in acute coronary syndrome patients. Clinical trials assessing the comparative efficacy of different doses of aspirin are scarce. This complex antiplatelet therapy landscape makes it difficult to identify the best aspirin dose for optimizing efficacy and minimizing risk of adverse events, while complying with the various guidelines and recommendations. Despite this fact, current evidence suggests that aspirin doses of 75-100 mg/day may offer the optimal benefit:risk ratio in acute coronary syndrome patients.
Keyword Acute coronary syndrome
aspirin
bleeding
clopidogrel
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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Created: Wed, 08 Apr 2015, 13:01:32 EST by Matthew Lamb on behalf of School of Medicine