Effect of oral hygiene interventions on opportunistic pathogens in patients after stroke

Lam, Otto L. T., McMillan, Anne S., Samaranayake, Lakshman P., Li, Leonard S. W. and McGrath, Colman (2013) Effect of oral hygiene interventions on opportunistic pathogens in patients after stroke. American Journal of Infection Control, 41 2: 149-154. doi:10.1016/j.ajic.2012.02.020

Author Lam, Otto L. T.
McMillan, Anne S.
Samaranayake, Lakshman P.
Li, Leonard S. W.
McGrath, Colman
Title Effect of oral hygiene interventions on opportunistic pathogens in patients after stroke
Journal name American Journal of Infection Control   Check publisher's open access policy
ISSN 0196-6553
Publication date 2013
Year available 2013
Sub-type Article (original research)
DOI 10.1016/j.ajic.2012.02.020
Open Access Status
Volume 41
Issue 2
Start page 149
End page 154
Total pages 6
Place of publication Philadelphia, PA United States
Publisher Mosby
Collection year 2014
Language eng
Abstract Background: Despite the role of the oral cavity as a reservoir of opportunistic pathogens for infection in patients following stroke, the evaluation of the effects of oral hygiene interventions has been largely neglected. Methods: This randomized clinical trial included 102 patients undergoing hospital-based rehabilitation for stroke. Patients were randomized to one of 3 groups: oral hygiene instruction (OHI) only; OHI and 0.2% chlorhexidine mouth rinse twice daily; or OHI, 0.2% chlorhexidine mouth rinse twice daily, and assisted brushing twice weekly. Oral samples were obtained at baseline and after 3 weeks for detection of Staphylococcus aureus, aerobic and facultatively anaerobic gram-negative bacilli, and yeasts. Results: Almost three-quarters (72.8%) of the patients harbored oral anaerobic gram-negative bacilli at baseline, and more than half had detectable S aureus (56.8%) and yeasts (59.3%). Percentage frequencies and viable counts of pathogens remained relatively stable during the course of the clinical trial, and no significant differences were observed among the 3 patient groups. Conclusions: In our study cohort, there was no significant difference in the effectiveness of the 3 different oral hygiene interventions on the prevalence or viable counts of oral opportunistic pathogens. Copyright
Keyword Bacteria
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 31 Mar 2015, 11:56:11 EST by Margot Dallinger on behalf of School of Dentistry