Dental plaque biofilm in oral health and disease

Seneviratne, C. J., Zhang, C. F. and Samaranayake, L. P. (2011) Dental plaque biofilm in oral health and disease. The Chinese Journal of Dental Research, 14 2: 87-94.

Author Seneviratne, C. J.
Zhang, C. F.
Samaranayake, L. P.
Title Dental plaque biofilm in oral health and disease
Journal name The Chinese Journal of Dental Research   Check publisher's open access policy
ISSN 1462-6446
1867-5646
Publication date 2011
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
Open Access Status
Volume 14
Issue 2
Start page 87
End page 94
Total pages 8
Place of publication New Malden, Surrey, United Kingdom
Publisher Quintessence Publishing
Language eng
Formatted abstract
Dental plaque is an archetypical biofilm composed of a complex microbial community. It is the aetiological agent for major dental diseases such as dental caries and periodontal disease. The clinical picture of these dental diseases is a net result of the cross-talk between the pathogenic dental plaque biofilm and the host tissue response. In the healthy state, both plaque biofilm and adjacent tissues maintain a delicate balance, establishing a harmonious relationship between the two. However, changes occur during the disease process that transform this 'healthy' dental plaque into a 'pathogenic' biofilm. Recent advances in molecular microbiology have improved the understanding of dental plaque biofilm and produced numerous clinical benefits. Therefore, it is imperative that clinicians keep abreast with these new developments in the field of dentistry. Better understanding of the molecular mechanisms behind dental diseases will facilitate the development of novel therapeutic strategies to establish a 'healthy dental plaque biofilm' by modulating both host and microbial factors. In this review, the present authors aim to summarise the current knowledge on dental plaque as a microbial biofilm and its properties in oral health and disease.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Dentistry Publications
 
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Created: Tue, 31 Mar 2015, 11:31:06 EST by Margot Dallinger on behalf of School of Dentistry