Corneal epithelial debridement for diagnosis and therapy of ocular surface disease

McGrath, Lindsay A. and Lee, Graham A. (2015) Corneal epithelial debridement for diagnosis and therapy of ocular surface disease. Clinical and Experimental Optometry, 98 2: 155-159. doi:10.1111/cxo.12213

Author McGrath, Lindsay A.
Lee, Graham A.
Title Corneal epithelial debridement for diagnosis and therapy of ocular surface disease
Journal name Clinical and Experimental Optometry   Check publisher's open access policy
ISSN 1444-0938
Publication date 2015-03-01
Year available 2014
Sub-type Article (original research)
DOI 10.1111/cxo.12213
Open Access Status
Volume 98
Issue 2
Start page 155
End page 159
Total pages 5
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2015
Language eng
Formatted abstract

There is a wide range of ocular surface conditions that can be diagnosed or treated with epithelial debridement. The purpose of this study is to analyse the indications, instrumentation and outcomes of corneal epithelial debridement for anterior segment pathology.


One hundred and thirty-three eyes of 129 patients with ocular surface disease were treated with epithelial debridement. Different methods were used, appropriate to the specific disease, aetiology and outcome measure.


The mean patient age was 56 years and 81 (60.9 per cent) were male. Sixty-two eyes (46.6 per cent) were undertaken for diagnosis and 71 (53.4 per cent) for therapy. Common indications for diagnostic corneal debridement included infective keratitis 48 (36.1 per cent), neoplasia 14 (10.5 per cent), while those for therapeutic corneal debridement included recurrent erosion 30 (22.5 per cent) and band keratopathy 16 (12.0 per cent). The most common post-operative complication was pain, occurring in all patients to some extent. Band keratopathy was seen to recur in two (12.5 per cent) of the treated eyes and there was a single relapse of recurrent erosion during the follow-up period.


The techniques presented can be undertaken in the office rather than a day procedural unit, improving time and cost-effectiveness for the ophthalmologist and patient.
Keyword Corneal debridement
Corneal scraping
Ocular surface disease
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 20 Oct 2014

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Official Audit
School of Medicine Publications
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