New Developments in Intracranial Stereotactic Radiotherapy for Metastases

Pinkham, Mark B, Whitfield, G.A and Brada, M (2015) New Developments in Intracranial Stereotactic Radiotherapy for Metastases. Clinical Oncology, 27 5: 316-323. doi:10.1016/j.clon.2015.01.007

Author Pinkham, Mark B
Whitfield, G.A
Brada, M
Title New Developments in Intracranial Stereotactic Radiotherapy for Metastases
Journal name Clinical Oncology   Check publisher's open access policy
ISSN 1433-2981
Publication date 2015-05
Year available 2015
Sub-type Article (original research)
DOI 10.1016/j.clon.2015.01.007
Volume 27
Issue 5
Start page 316
End page 323
Total pages 8
Place of publication London, United Kingdom
Publisher Elsevier Ltd
Collection year 2016
Language eng
Abstract Brain metastases are common and the prognosis for patients with multiple brain metastases treated with whole brain radiotherapy is limited. As systemic disease control continues to improve, the expectations of radiotherapy for brain metastases are growing. Stereotactic radiosurgery (SRS) as a high precision localised irradiation given in a single fraction prolongs survival in patients with a single brain metastasis and functional independence in those with up to three brain metastases. SRS technology has become commonplace and is available in many radiation oncology and neurosurgery departments. With increasing use there is a need for appropriate patient selection, refinement of dose-fractionation and safe integration of SRS with other treatment modalities. We review the evidence for current practice and new developments in the field, with a specific focus on patient-relevant outcomes.
Keyword Brain metastases
Gamma knife
Stereotactic radiosurgery
Stereotactic radiotherapy
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
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