We endorse Carlsten et al’s analysis of the major limitations in using genomic information to reduce social disparities in smoking prevalence. We would stress a major limitation in the use of genetic information to tailor smoking cessation assistance to smokers, namely, that smoking risk and likelihood of cessation is likely to involve many risk alleles of small effect which makes it difficult to predict differential responses to smoking cessation interventions...
Invited commentary: Reply to Carlsten, Halperin, Crouch, Burke, "Personalized Medicine and Tobacco-Related Health Disparities: Is There a Role for Genetics?", Ann Fam Med 2011 9:366-371; doi:10.1370/afm.1244
Letter to editor, brief commentary or brief communication