Topical CPP-ACP crèmes: beyond caries prevention

Walsh, Laurence J. (2014) Topical CPP-ACP crèmes: beyond caries prevention. International Dentistry South Africa, 4 5: 26-32.

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Author Walsh, Laurence J.
Title Topical CPP-ACP crèmes: beyond caries prevention
Journal name International Dentistry South Africa
ISSN 1818-6734
Publication date 2014-11-01
Year available 2014
Sub-type Article (original research)
Open Access Status
Volume 4
Issue 5
Start page 26
End page 32
Total pages 7
Place of publication Wendywood, South Africa
Publisher Modern Dentistry Media
Collection year 2015
Language eng
Formatted abstract
Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) is a unique naturally derived protein-based remineralizing technology which is used globally in chewing gums (such Recaldent ™) and topical crèmes (such as GC Tooth Mousse ™. and Tooth Mousse Plus ™). Phosphopeptides are derived from milk caseins are complexed with amorphous calcium phosphate, to form stable complexes which are nanoparticles of some 2 nm in diameter with a large surface area (Cross et al. 2006). CPP-ACP complexes act as biological calcium phosphate delivery vehicles, and are able to boost levels of bioavailable calcium and phosphate in saliva and plaque fluid without causing indiscriminate precipitation of calcium salts. This makes this material particularly effective in the remineralization of early enamel lesions, and in the treatment of other types of enamel opacities. As such, the range of clinical applications now extends beyond altering the demin/remin balance for human enamel to treating hypoplastic enamel and other types of enamel opacities
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Official Audit
School of Dentistry Publications
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Created: Wed, 18 Feb 2015, 16:32:43 EST by Professor Laurence Walsh on behalf of School of Dentistry