The effect of paired associative stimulation on fatigue resistance

Kumpulainen, Susanne, Peltonen, Jussi, Gruber, Markus, Cresswell, Andrew, Peurala, Sinikka, Linnamo, Vesa and Avela, Janne (2015) The effect of paired associative stimulation on fatigue resistance. Neuroscience Research, 95 59-65. doi:10.1016/j.neures.2015.01.015


Author Kumpulainen, Susanne
Peltonen, Jussi
Gruber, Markus
Cresswell, Andrew
Peurala, Sinikka
Linnamo, Vesa
Avela, Janne
Title The effect of paired associative stimulation on fatigue resistance
Journal name Neuroscience Research   Check publisher's open access policy
ISSN 0168-0102
1872-8111
Publication date 2015-06
Year available 2015
Sub-type Article (original research)
DOI 10.1016/j.neures.2015.01.015
Open Access Status
Volume 95
Start page 59
End page 65
Total pages 7
Place of publication Shannon, County Clare, Ireland
Publisher Elsevier Ireland
Collection year 2016
Language eng
Formatted abstract
Paired associative stimulation (PAS) is a non-invasive stimulation method developed to induce bidirectional changes in the excitability of the cortical projections to the target muscles. However, very few studies have shown an association between changes in motor evoked potentials (MEP) after PAS and behavioral changes in healthy subjects. In the present study we hypothesized that the functional relevance of PAS can be seen during fatiguing exercise, since there is always a central contribution to the development of fatigue. Transcranial magnetic stimulation was applied over the motor cortex to measure changes in the MEPs of the soleus muscle before and after PAS. Furthermore, fatigue resistance was tested during 15 s sustained maximal isometric contractions before and after PAS. On average, fatigue resistance did not change after PAS, however the change in excitability correlated significantly with the change in fatigue resistance. Discussion: Functionality of PAS intervention was not demonstrated in this study. However, the observed relationship between excitability and fatigue resistance suggests that PAS might have affected central fatigue during short maximal contractions.
Keyword Fatigue
Central fatigue
Motor cortex
Transcranial magnetic stimulation
Paired associative stimulation
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Human Movement and Nutrition Sciences Publications
 
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Created: Mon, 16 Feb 2015, 15:41:41 EST by Sandrine Ducrot on behalf of School of Human Movement and Nutrition Sciences