Hepatitis E virus: do locally acquired infections in Australia necessitate laboratory testing in acute hepatitis patients with no overseas travel history?

Shrestha, Ashish C., Faddy, Helen M., Flower, Robert L. P., Seed, Clive R. and Keller, Anthony J. (2015) Hepatitis E virus: do locally acquired infections in Australia necessitate laboratory testing in acute hepatitis patients with no overseas travel history?. Pathology, 47 2: 97-100. doi:10.1097/PAT.0000000000000229


Author Shrestha, Ashish C.
Faddy, Helen M.
Flower, Robert L. P.
Seed, Clive R.
Keller, Anthony J.
Title Hepatitis E virus: do locally acquired infections in Australia necessitate laboratory testing in acute hepatitis patients with no overseas travel history?
Journal name Pathology   Check publisher's open access policy
ISSN 0031-3025
1465-3931
Publication date 2015-02
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/PAT.0000000000000229
Open Access Status DOI
Volume 47
Issue 2
Start page 97
End page 100
Total pages 4
Place of publication London, United Kingdom
Publisher Lippincott Williams & Wilkins [Elsevier]
Collection year 2016
Language eng
Abstract Hepatitis E virus (HEV) is emerging as a global public health threat. Water-borne HEV outbreaks are common in developing countries and are associated with genotypes 1 and 2. In industrialised countries, sporadic cases of zoonotic transmission associated with genotypes 3 and 4 are increasingly being reported. Transfusion- and transplantation-transmitted HEV have been documented, although ingestion of contaminated food is thought to be the major transmission route. Severe disease is possible and chronic hepatitis infection occurs in solid-organ-transplant recipients and in patients with immunosuppressive disorders. In Australia, HEV cases are mainly travellers returning from disease endemic countries. Indeed, there are few reported cases of locally acquired HEV. Pigs in Australia have been shown to be infected with HEV, which indicates the possibility of zoonotic transmission. The extent of locally acquired infection is not known, however it may be greater than expected and may necessitate laboratory testing in patients reporting no overseas travel.
Keyword Acute hepatitis
Australia
Chronic hepatitis
Hepatitis E virus
Laboratory testing
Seroprevalence
Traveller
Zoonotic
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Medicine Publications
 
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