Assessment of breast cancer-related Lymphedema: a comparison of moisture meter and spot bioimpedance measurement

Czerniec, Sharon Anne, Ward, Leigh C. and Kilbreath, Sharon L. (2015) Assessment of breast cancer-related Lymphedema: a comparison of moisture meter and spot bioimpedance measurement. Lymphatic Research and Biology, 13 1: 10-19. doi:10.1089/lrb.2014.0032


Author Czerniec, Sharon Anne
Ward, Leigh C.
Kilbreath, Sharon L.
Title Assessment of breast cancer-related Lymphedema: a comparison of moisture meter and spot bioimpedance measurement
Journal name Lymphatic Research and Biology   Check publisher's open access policy
ISSN 1557-8585
1539-6851
Publication date 2015-03
Year available 2015
Sub-type Article (original research)
DOI 10.1089/lrb.2014.0032
Open Access Status
Volume 13
Issue 1
Start page 10
End page 19
Total pages 10
Place of publication New Rochelle, NY, United States
Publisher Mary Ann Liebert
Collection year 2016
Language eng
Formatted abstract
Background: Tissue dielectric constant (TDC) and spot bioimpedance measurement (BIA) have a role in the assessment of tissue composition changes in breast cancer-related lymphedema (BCRL). Our aims were to determine whether TDC and spot BIA measures could detect inter-limb differences in BCRL, explore the relationship between methods, and establish the intra-rater reliability and technical error of measurement for TDC.

Methods and Results: Women with (n=20) and without (n=4) unilateral BCRL participated. Circumference, TDC, and spot BIA measures were completed on the most affected region of the arm for BCRL participants and at a standardized forearm point in women without lymphedema. All measures were compared to measurements from an identical location on the contralateral arm. The affected arm differed significantly to the unaffected arm of women with BCRL for TDC and spot BIA measures. The median (IQR) differences were: extra-small probe 5.75 (3.10–8.21), small probe 3.50 (1.16–6.89), medium probe 5.08 (0.88–10.91), and for spot BIA measurement (−35.20 Ω; −59.75 to −14.85 Ω). The small and medium TDC probe measures were moderately correlated to spot bioimpedance measurements (r=−0.54 and r=−0.43, respectively). Intra-rater reliability coefficients (ICC2,1) of TDC measures ranged from 0.50 (95% CI: 0.12–0.75) to 0.92 (0.82–0.96). TDC technical error of measurement for women with lymphedema varied from 10.5% to 13.3%.

Conclusions: Both TDC and spot bioimpedance may have a role in clinical assessment of tissue compositional change in BCRL. Their relationship with tissue composition, assessed by imaging, is now required.
Keyword Breast cancer
Lymphedema
Tissue dielectric constant (TDC)
Spot bioimpedance measurement (BIA)
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 13 Feb 2015, 10:32:45 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences