Anatomy and neurophysiology of cough: CHEST guideline and expert panel report

Canning, Brendan J., Chang, Anne B., Bolser, Donald C., Smith, Jaclyn A., Mazzone, Stuart B. and McGarvey, Lorcan (2014) Anatomy and neurophysiology of cough: CHEST guideline and expert panel report. Chest, 146 6: 1633-1648. doi:10.1378/chest.14-1481


Author Canning, Brendan J.
Chang, Anne B.
Bolser, Donald C.
Smith, Jaclyn A.
Mazzone, Stuart B.
McGarvey, Lorcan
Title Anatomy and neurophysiology of cough: CHEST guideline and expert panel report
Journal name Chest   Check publisher's open access policy
ISSN 0012-3692
1931-3543
Publication date 2014-12-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1378/chest.14-1481
Open Access Status
Volume 146
Issue 6
Start page 1633
End page 1648
Total pages 16
Place of publication Northbrook, IL United States
Publisher American College of Chest Physicians
Collection year 2015
Language eng
Formatted abstract
Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated sensory nerves play essential roles in regulating cough. These vagal sensory nerves terminate primarily in the larynx, trachea, carina, and large intrapulmonary bronchi. Other bronchopulmonary sensory nerves, sensory nerves innervating other viscera, as well as somatosensory nerves innervating the chest wall, diaphragm, and abdominal musculature regulate cough patterning and cough sensitivity. The responsiveness and morphology of the airway vagal sensory nerve subtypes and the extrapulmonary sensory nerves that regulate coughing are described. The brainstem and higher brain control systems that process this sensory information are complex, but our current understanding of them is considerable and increasing. The relevance of these neural systems to clinical phenomena, such as urge to cough and psychologic methods for treatment of dystussia, is high, and modern imaging methods have revealed potential neural substrates for some features of cough in the human.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Biomedical Sciences Publications
 
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Created: Wed, 28 Jan 2015, 07:03:50 EST by Dr Stuart Mazzone on behalf of School of Biomedical Sciences