Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: gestational age versus niche

Ryan, Jennifer M., Matigian, Nicholas, Pelekanos, Rebecca A., Jesuadian, Samuel, Wells, Christine A. and Fisk, Nicholas M. (2014) Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: gestational age versus niche. Genomics Data, 2 382-385. doi:10.1016/j.gdata.2014.10.016


Author Ryan, Jennifer M.
Matigian, Nicholas
Pelekanos, Rebecca A.
Jesuadian, Samuel
Wells, Christine A.
Fisk, Nicholas M.
Title Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: gestational age versus niche
Journal name Genomics Data   Check publisher's open access policy
ISSN 2213-5960
Publication date 2014-12
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.gdata.2014.10.016
Open Access Status DOI
Volume 2
Start page 382
End page 385
Total pages 4
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2015
Language eng
Abstract Early fetal and placental MSCs have translationally-advantageous characteristics compared to later pregnancy MSCs. During the first trimester, the fetus and placenta grow rapidly with divergent developmental requirements, but studies comparing mesenchymal stem cells (MSCs) from different origins have paid little attention to the effect of gestational age over this temporal window. Here we present the transcriptome through first trimester development of MSC isolated from fetal bone marrow (BM) or placental structures. Samples were collected weekly from 8 to 12 weeks. The raw microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-1224. Additionally, the data have been integrated into the stem cell collaboration platform www.Stemformatics.org. These data provide a valuable resource for developmental biology and stem cell investigation.
Keyword Fetal
Placental
Mesenchymal stem/stromal cells
First trimester
Gestational age
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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