Early-life risk factors for chronic nonrespiratory diseases

Chacko, Archana, Carpenter, David O., Callaway, Leonie and Sly, Peter D. (2015) Early-life risk factors for chronic nonrespiratory diseases. European Respiratory Journal, 45 1: 244-259. doi:10.1183/09031936.00070214

Author Chacko, Archana
Carpenter, David O.
Callaway, Leonie
Sly, Peter D.
Title Early-life risk factors for chronic nonrespiratory diseases
Journal name European Respiratory Journal   Check publisher's open access policy
ISSN 1399-3003
Publication date 2015-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1183/09031936.00070214
Open Access Status
Volume 45
Issue 1
Start page 244
End page 259
Total pages 16
Place of publication Lausanne, Switzerland
Publisher European Respiratory Society
Collection year 2015
Language eng
Abstract We have witnessed a change in disease patterns contributing to the global burden of disease, with a shift from early childhood deaths due to the classic infectious communicable diseases to years lived with disability from chronic noncommunicable diseases. In both developing and developed countries, the years lived with disability attributable to chronic disease have increased: cardiovascular diseases by 17.7%; chronic respiratory disease by 8.5%; neurological conditions by 12.2%; diabetes by 30.0%; and mental and behavioural disorders by 5.0% over the past 20 years. Recognition of the contribution made by adverse environmental exposures in early life to noncommunicable diseases in later life is increasing. These early-life exposures appear to contribute to both chronic respiratory and chronic nonrespiratory diseases. In this State of the Art article, we aim to examine early-life environmental exposures that have an epidemiological association with chronic nonrespiratory diseases, such as obesity and type II diabetes, cardiovascular disease, and neurocognitive and behavioural problems. We will highlight the potential overlap in environmental risks with respiratory diseases, and point out knowledge gaps and research opportunities.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 13 Nov 2014

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
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