Aetiologies of diarrhoea in adults from urban and rural treatment facilities in Bangladesh

Ferdous, F., Ahmed, S., Farzana, F. D., Das, J., Malek, M. A., Sumon, D. K., Salam, M. A. and Faruque, A. S. G (2014) Aetiologies of diarrhoea in adults from urban and rural treatment facilities in Bangladesh. Epidemiology and Infection, 143 7: 1377-1387. doi:10.1017/S0950268814002283

Author Ferdous, F.
Ahmed, S.
Farzana, F. D.
Das, J.
Malek, M. A.
Sumon, D. K.
Salam, M. A.
Faruque, A. S. G
Title Aetiologies of diarrhoea in adults from urban and rural treatment facilities in Bangladesh
Journal name Epidemiology and Infection   Check publisher's open access policy
ISSN 0950-2688
Publication date 2014-09-15
Year available 2014
Sub-type Article (original research)
DOI 10.1017/S0950268814002283
Open Access Status
Volume 143
Issue 7
Start page 1377
End page 1387
Total pages 11
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Collection year 2015
Language eng
Formatted abstract
The objective of our analysis was to describe the aetiology, clinical features, and socio-demographic background of adults with diarrhoea attending different urban and rural diarrhoeal disease hospitals in Bangladesh. Between January 2010 and December 2011, a total of 5054 adult diarrhoeal patients aged ⩾20 years were enrolled into the Diarrhoeal Disease Surveillance Systems at four different hospitals (two rural and two urban) of Bangladesh. Middle-aged [adjusted odds ratio (aOR) 0·28, 95% confidence interval (CI) 0·23–0·35, P < 0·001] and elderly (aOR 0·15, 95% CI 0·11–0·20, P < 0·001) patients were more likely to present to rural diarrhoeal disease facilities than urban ones. Vibrio cholerae was the most commonly isolated pathogen (16%) of the four pathogens tested followed by rotavirus (5%), enterotoxigenic Escherichia coli (ETEC) (4%), and Shigella (4%). Of these pathogens, V. cholerae (19% vs. 11%, P < 0·001), ETEC (9% vs. 4%, P < 0·001), and rotavirus (5% vs. 3%, P = 0·013) were more commonly detected from patients presenting to urban hospitals than rural hospitals, but Shigella was more frequently isolated from patients presenting to rural hospitals than urban hospitals (7% vs. 2%, P < 0·001). The isolation rate of Shigella was higher in the elderly than in younger adults (8% vs. 3%, P < 0·001). Some or severe dehydration was higher in urban adults than rural adults (P < 0·001). Our findings indicate that despite economic and other progress made, conditions facilitating transmission of V. cholerae and Shigella prevail in adults with diarrhoea in Bangladesh and further efforts are needed to control these infections.
Keyword Adult
Middle aged
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online: 15 September 2014.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
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Created: Thu, 08 Jan 2015, 15:32:55 EST by Nyree Divitini on behalf of School of Public Health