The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014) The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 101: 313-322.

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Name Description MIMEType Size Downloads
Author Rivera-Hernandez, Tania
Carnathan, Diane G.
Moyle, Peter M.
Toth, Istvan
West, Nicholas P.
Young, Paul L.
Silvestri, Guido
Walker, Mark J.
Title The contribution of non-human primate models to the development of human vaccines
Journal name Discovery Medicine   Check publisher's open access policy
ISSN 1539-6509
1944-7930
Publication date 2014-12
Sub-type Critical review of research, literature review, critical commentary
Open Access Status
Volume 18
Issue 101
Start page 313
End page 322
Total pages 10
Place of publication Timonium, MD, United States
Publisher Solariz
Collection year 2015
Language eng
Formatted abstract
The non-human primates (NHPs) model in biomedical research has contributed to the study of human infectious, autoimmune, oncogenic, and neurological diseases. This review focuses on the importance of NHP models in vaccine development for tuberculosis, pertussis, Dengue, group A streptococcus (Streptococcus pyogenes) infection, HIV infection, and certain diseases in the elderly (influenza, for example). From understanding disease pathogenesis and mechanisms of protection, to assessing vaccine safety and efficacy, we discuss selected cases where the importance of the use of NHP models is highlighted.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Chemistry and Molecular Biosciences
School of Pharmacy Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 02 Jan 2015, 09:15:38 EST by Peter Moyle on behalf of School of Chemistry & Molecular Biosciences