Alcohol-containing mouthwash and oral cancer risk: a review of current evidence

Currie, S. and Farah, C. (2014) Alcohol-containing mouthwash and oral cancer risk: a review of current evidence. OA Alcohol, 2 1: 4.1-4.9.

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Author Currie, S.
Farah, C.
Title Alcohol-containing mouthwash and oral cancer risk: a review of current evidence
Journal name OA Alcohol   Check publisher's open access policy
ISSN 2053-0285
Publication date 2014-02-10
Sub-type Critical review of research, literature review, critical commentary
Open Access Status File (Publisher version)
Volume 2
Issue 1
Start page 4.1
End page 4.9
Total pages 9
Place of publication London, United Kingdom
Publisher Open Access Publishing London
Collection year 2015
Language eng
Formatted abstract
Introduction
The existence or lack of an association between the use of alcohol-containing mouthwashes and the development of oral squamous cell carcinoma remains a significantly contentious issue within the scientific community. The published literature on the topic includes both epidemiological studies assessing associations on a population level and mechanistic studies investigating the local effects of alcohol-containing mouthwashes in both in vitro and in vivo environments, as well as reviews evaluating, comparing and synthesising these results. Despite a broad base of evidence, there remains no clear academic consensus with regard to the relationship between alcohol-containing mouthwashes and oral squamous cell carcinoma. This review aims to present and evaluate the evidence for and against any association.

Conclusion
While there is a lack of consistent evidence, it is advisable for clinicians to promote the use of non-alcoholic mouthwashes in order to minimise any potential increase in risk, and discourage long-term use of high alcohol-containing products.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2015 Collection
School of Dentistry Publications
 
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Created: Mon, 22 Dec 2014, 12:05:25 EST by Roheen Gill on behalf of School of Dentistry