A comparison of segmental and wrist-to-ankle methodologies of bioimpedance analysis

Thomas, BJ, Cornish, BH, Ward, LC and Patterson, MA (1998) A comparison of segmental and wrist-to-ankle methodologies of bioimpedance analysis. Applied Radiation And Isotopes, 49 5-6: 477-478. doi:10.1016/S0969-8043(97)00058-4

Author Thomas, BJ
Cornish, BH
Ward, LC
Patterson, MA
Title A comparison of segmental and wrist-to-ankle methodologies of bioimpedance analysis
Journal name Applied Radiation And Isotopes   Check publisher's open access policy
ISSN 0969-8043
Publication date 1998
Sub-type Article (original research)
DOI 10.1016/S0969-8043(97)00058-4
Volume 49
Issue 5-6
Start page 477
End page 478
Total pages 2
Publisher Elsevier Sci Ltd
Language eng
Abstract The common approach of bioelectrical impedance analysis to estimate body water uses a wrist-to-ankle methodology which, although not indicated by theory, has the advantage of ease of application particularly for clinical studies involving patients with debilitating diseases. A number of authors have suggested the use of a segmental protocol in which the impedances of the trunk and limbs are measured separately to provide a methodology more in keeping with basic theory. The segmental protocol hits not, however, been generally adopted, partly because of the increased complexity involved in its application, and partly because studies comparing the two methodologies have not clearly demonstrated a significant improvement from the segmental methodology. We have conducted a small pilot study involving ten subjects to investigate the efficacy of the two methodologies in a group of normal subjects. The study did not require the independent measure of body water, by for example isotope dilution, as the subjects were maintained in a state of constant hydration with only the distribution between limbs and trunk changing as a result of change in posture. The results demonstrate a significant difference between the two methodologies in predicting the expected constancy of body water in this study, with the segmental methodology indicating a mean percentage change in extracellular water of -2.2%; which was not significantly different from the expected null result, whereas the wrist-to-ankle methodology indicated a mean percentage change in extracellular water of -6.6%. This is significantly different from the null result, and from the value obtained from the segmental methodology (p = 0.006). Similar results were obtained using estimates of total body water from the two methodologies. (C) 1998 Elsevier Science Ltd. All rights reserved.
Keyword Chemistry, Inorganic & Nuclear
Nuclear Science & Technology
Radiology, Nuclear Medicine & Medical Imaging
Bioelectrical-impedance Analysis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Chemistry and Molecular Biosciences
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Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 13 Aug 2007, 10:23:15 EST