Host resistance in cattle to infestation with the cattle tick Rhipicephalus microplus

Jonsson, N. N., Piper, E. K. and Constantinoiu, C. C. (2014) Host resistance in cattle to infestation with the cattle tick Rhipicephalus microplus. Parasite Immunology, 36 11: 551-557. doi:10.1111/pim.12140


Author Jonsson, N. N.
Piper, E. K.
Constantinoiu, C. C.
Title Host resistance in cattle to infestation with the cattle tick Rhipicephalus microplus
Formatted title
Host resistance in cattle to infestation with the cattle tick Rhipicephalus microplus
Journal name Parasite Immunology   Check publisher's open access policy
ISSN 0141-9838
1365-3024
Publication date 2014-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/pim.12140
Open Access Status
Volume 36
Issue 11
Start page 551
End page 557
Total pages 7
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell
Collection year 2015
Language eng
Formatted abstract
Resistance to Rhipicephalus microplus infestation in cattle has many effector mechanisms, each of which is likely to be modulated by complex, interacting factors. Some of the mechanisms of host resistance and their modulating factors have been identified and quantified, although much remains to be explained. The variation in resistance to tick infestation is most marked between Bos taurus and Bos indicus cattle, taurine cattle given the same exposure carrying between five and 10 times as many ticks as indicine cattle. Tick resistance is mostly manifest against attaching larvae, which attempt to feed often and without success, death occurring mostly within 24 h of finding a host. There is evidence of innate and adaptive immune response to tick infestation, and it appears that the relative importance of each differs between indicine and taurine cattle. There is conflicting information regarding the role of humoral immunity in tick resistance, and recent studies indicate that strong IgG responses to tick antigens are not protective. A strong T-cell-mediated response directed against larval stages, as mounted by indicine cattle, seems to be protective. Variation in the extracellular matrix of skin (epidermal growth factors, collagens and other matrix components such as lumican) also contributes to variation in host resistance.
Keyword Boophilus microplus
ELISA/Enzyme-linked immunosorbent assay
Expression profiling
Flow cytometry
Gene expression
Immunogenetics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Veterinary Science Publications
 
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