Probiotics and Pregnancy

Gomez Arango, Luisa F., Barrett, Helen L., Callaway, Leonie K. and Nitert, Marloes D. (2014) Probiotics and Pregnancy. Current Diabetes Reports, 15 1: 567.1-567.9. doi:10.1007/s11892-014-0567-0

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Author Gomez Arango, Luisa F.
Barrett, Helen L.
Callaway, Leonie K.
Nitert, Marloes D.
Title Probiotics and Pregnancy
Journal name Current Diabetes Reports   Check publisher's open access policy
ISSN 1534-4827
Publication date 2014-11-11
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s11892-014-0567-0
Open Access Status Not Open Access
Volume 15
Issue 1
Start page 567.1
End page 567.9
Total pages 9
Place of publication Philadelphia, PA United States
Publisher Springer Healthcare
Collection year 2015
Language eng
Formatted abstract
Complications of pregnancy are associated with adverse outcomes for mother and baby in the short and long term. The gut microbiome has been identified as a key factor for maintaining health outside of pregnancy and could contribute to pregnancy complications. In addition, the vaginal and the recently revealed placental microbiome are altered in pregnancy and may play a role in pregnancy complications. Probiotic supplementation could help to regulate the unbalanced microflora composition observed in obesity and diabetes. Here, the impact of probiotic supplementation during pregnancy and infancy is reviewed. There are indications for a protective role in preeclampsia, gestational diabetes mellitus, vaginal infections, maternal and infant weight gain and allergic diseases. Large, well-designed randomised controlled clinical trials along with metagenomic analysis are needed to establish the role of probiotics in adverse pregnancy and infancy outcomes.
Keyword Infant outcomes
Maternal microbiome
Pregnancy complications
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2015 Collection
School of Medicine Publications
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