Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries

Mattei, Cesar, Vetter, Irina, Eisenblatter, Anneka, Krock, Bernd, Ebbecke, Martin, Desel, Herbert and Zimmermann, Katharina (2014) Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries. Toxicon, 91 76-83. doi:10.1016/j.toxicon.2014.10.016


Author Mattei, Cesar
Vetter, Irina
Eisenblatter, Anneka
Krock, Bernd
Ebbecke, Martin
Desel, Herbert
Zimmermann, Katharina
Title Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries
Journal name Toxicon   Check publisher's open access policy
ISSN 1879-3150
0041-0101
Publication date 2014-12-01
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.toxicon.2014.10.016
Volume 91
Start page 76
End page 83
Total pages 8
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon Press
Collection year 2015
Language eng
Formatted abstract
Toxin-producing microalgae are thriving worldwide due to coral reef destruction and global warming with major consequences on ecosystems, international trade and human health. Microalgae belonging to the family of flagellate protists, in particular dinoflagellates, secrete a variety of high-molecular-weight polyether toxins that accumulate through the marine food chain to cause disease in humans by acting as sodium channel activator toxins; ciguatera is the most frequent seafood-borne illness worldwide with 50,000 to 500,000 global incidences per annum and is usually limited to endemic areas located between 35° northern and 35° southern latitude. The rising global incidence frequency renders it a major human health problem, because no curative treatment is available yet and reliable detection assays are lacking. During the last decade ciguatera has increasingly become endemic in previously unaffected areas for two reasons: first global warming has contributed to the emergence of dinoflagellate species in subtropical and even temperate regions that previously had been constrained to tropical areas and second: in Europe globalization of fishing industry and tourism has led to a progressive increase in the number of ciguatera cases and a lack of awareness among medical personnel contributes to under-reporting. We review, through a recent ciguatera outbreak in Germany, the risk for ciguatera poisoning in Europe and highlight characteristic symptoms, current knowledge about disease pathomechanisms and treatment options.
Keyword Ciguatera
Ciguatoxins
Contaminated fish
Na+ channel
Sea food intoxication
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Institute for Molecular Bioscience - Publications
 
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