Association of sedentary behaviour with metabolic syndrome: a meta-analysis

Edwardson, Charlotte L., Gorely, Trish, Davies, Melanie J., Gray, Laura J., Khunti, Kamlesh, Wilmot, Emma G., Yates, Thomas and Biddle, Stuart J. H. (2012) Association of sedentary behaviour with metabolic syndrome: a meta-analysis. PLoS One, 7 4: e34916.1-e34916.5. doi:10.1371/journal.pone.0034916

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads

Author Edwardson, Charlotte L.
Gorely, Trish
Davies, Melanie J.
Gray, Laura J.
Khunti, Kamlesh
Wilmot, Emma G.
Yates, Thomas
Biddle, Stuart J. H.
Title Association of sedentary behaviour with metabolic syndrome: a meta-analysis
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2012-04-13
Sub-type Article (original research)
DOI 10.1371/journal.pone.0034916
Open Access Status DOI
Volume 7
Issue 4
Start page e34916.1
End page e34916.5
Total pages 5
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Language eng
Formatted abstract
Background: In recent years there has been a growing interest in the relationship between sedentary behaviour (sitting) and health outcomes. Only recently have there been studies assessing the association between time spent in sedentary behaviour and the metabolic syndrome. The aim of this study is to quantify the association between sedentary behaviour and the metabolic syndrome in adults using meta-analysis.

Methodology/Principal Findings: Medline, Embase and the Cochrane Library were searched using medical subject headings and key words related to sedentary behaviours and the metabolic syndrome. Reference lists of relevant articles and personal databases were hand searched. Inclusion criteria were: (1) cross sectional or prospective design; (2) include adults ≥18 years of age; (3) self-reported or objectively measured sedentary time; and (4) an outcome measure of metabolic syndrome. Odds Ratio (OR) and 95% confidence intervals for metabolic syndrome comparing the highest level of sedentary behaviour to the lowest were extracted for each study. Data were pooled using random effects models to take into account heterogeneity between studies. Ten cross-sectional studies (n = 21393 participants), one high, four moderate and five poor quality, were identified. Greater time spent sedentary increased the odds of metabolic syndrome by 73% (OR 1.73, 95% CI 1.55-1.94, p<0.0001). There were no differences for subgroups of sex, sedentary behaviour measure, metabolic syndrome definition, study quality or country income. There was no evidence of statistical heterogeneity (I 2 = 0.0%, p = 0.61) or publication bias (Eggers test t = 1.05, p = 0.32).

Conclusions: People who spend higher amounts of time in sedentary behaviours have greater odds of having metabolic syndrome. Reducing sedentary behaviours is potentially important for the prevention of metabolic syndrome.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 101 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 120 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 04 Dec 2014, 09:21:01 EST by Sandrine Ducrot on behalf of School of Human Movement and Nutrition Sciences