Vision modulates corticospinal suppression in a functionally specific manner during movement of the opposite limb

Carson, Richard G. and Ruddy, Kathy L. (2012) Vision modulates corticospinal suppression in a functionally specific manner during movement of the opposite limb. Journal of Neuroscience, 32 2: 646-652. doi:10.1523/JNEUROSCI.4435-11.2012

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Author Carson, Richard G.
Ruddy, Kathy L.
Title Vision modulates corticospinal suppression in a functionally specific manner during movement of the opposite limb
Journal name Journal of Neuroscience   Check publisher's open access policy
ISSN 0270-6474
1529-2401
Publication date 2012-01-11
Sub-type Article (original research)
DOI 10.1523/JNEUROSCI.4435-11.2012
Open Access Status File (Publisher version)
Volume 32
Issue 2
Start page 646
End page 652
Total pages 7
Place of publication Washington, DC, United States
Publisher Society for Neuroscience
Language eng
Abstract The effect of vision on the excitability of corticospinal projections to the flexor carpi radialis (FCR) and extensor carpi radialis (ECR) muscles of right human forearm was investigated before and during discrete movement of the opposite limb. An external force opposed the initial phase of the movement (wrist flexion) and assisted the reverse phase, so that recruitment of the wrist extensors was minimized. Three conditions were used as follows: viewing the inactive right limb (Vision), viewing the mirror image of the moving left limb (Mirror), and with vision of the right limb occluded (No Vision). Transcranial magnetic stimulation was delivered to the left motor cortex: before, at the onset of, or during the left limb movement to obtain motor evoked potentials (MEPs) in the muscles of the right forearm. At and following movement onset, MEPs obtained in the right FCR were smaller in the Vision condition than in the Mirror and No Vision conditions. A distinct pattern of variation was obtained for the ECR. In all conditions, MEPs in this muscle were elevated upon or following movement of the opposite limb. An additional analysis of ipsilateral silent periods indicated that interhemispheric inhibition plays a role in mediating these effects. Activity-dependent changes in corticospinal output to a resting limb during discrete actions of the opposite limb are thus directly contingent upon where one looks. Furthermore, the extent to which vision exerts an influence upon projections to specific muscles varies in accordance with the functional contribution of their homologs to the intended action.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
 
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Created: Wed, 03 Dec 2014, 09:35:42 EST by Sandrine Ducrot on behalf of School of Human Movement and Nutrition Sciences